2ITM
Crystal structure of the E. coli xylulose kinase complexed with xylulose
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004856 | molecular_function | D-xylulokinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0005997 | biological_process | xylulose metabolic process |
| A | 0005998 | biological_process | xylulose catabolic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| A | 0042732 | biological_process | D-xylose metabolic process |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0042843 | biological_process | D-xylose catabolic process |
| A | 0046835 | biological_process | carbohydrate phosphorylation |
| A | 0103020 | molecular_function | 1-deoxy-D-xylulose kinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004856 | molecular_function | D-xylulokinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0005997 | biological_process | xylulose metabolic process |
| B | 0005998 | biological_process | xylulose catabolic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016773 | molecular_function | phosphotransferase activity, alcohol group as acceptor |
| B | 0042732 | biological_process | D-xylose metabolic process |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0042843 | biological_process | D-xylose catabolic process |
| B | 0046835 | biological_process | carbohydrate phosphorylation |
| B | 0103020 | molecular_function | 1-deoxy-D-xylulose kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE XUL A 4930 |
| Chain | Residue |
| A | MET77 |
| A | HIS78 |
| A | TRP96 |
| A | ASP233 |
| A | ASN234 |
| A | MET288 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE XUL B 4931 |
| Chain | Residue |
| B | ASP233 |
| B | ASN234 |
| B | MET288 |
| B | HOH5058 |
| B | HOH5113 |
| B | HOH5116 |
| B | MET77 |
| B | HIS78 |
| B | TRP96 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 4932 |
| Chain | Residue |
| B | GLY254 |
| B | THR255 |
| B | GLY394 |
| B | GLY395 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 4931 |
| Chain | Residue |
| A | ARG196 |
| A | HOH5150 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NH4 B 4933 |
| Chain | Residue |
| B | ARG137 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NH4 B 4935 |
| Chain | Residue |
| A | ASN309 |
| A | VAL310 |
| A | ARG398 |
| B | ARG54 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NH4 A 4935 |
| Chain | Residue |
| A | ASP197 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NH4 A 4938 |
| Chain | Residue |
| A | VAL33 |
Functional Information from PROSITE/UniProt
| site_id | PS00445 |
| Number of Residues | 21 |
| Details | FGGY_KINASES_2 FGGY family of carbohydrate kinases signature 2. GvFFGLthqhgpn.ELARAVLE |
| Chain | Residue | Details |
| A | GLY347-GLU367 |
| site_id | PS00933 |
| Number of Residues | 13 |
| Details | FGGY_KINASES_1 FGGY family of carbohydrate kinases signature 1. GfTapKLLWVQRH |
| Chain | Residue | Details |
| A | GLY126-HIS138 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_02220","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17123542","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_02220","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17123542","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"HAMAP-Rule","id":"MF_02220","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17123542","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
