2ISL
BluB bound to reduced flavin (FMNH2) and molecular oxygen. (clear crystal form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0009236 | biological_process | cobalamin biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0009236 | biological_process | cobalamin biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0009236 | biological_process | cobalamin biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| C | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0009236 | biological_process | cobalamin biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| D | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| E | 0000166 | molecular_function | nucleotide binding |
| E | 0009236 | biological_process | cobalamin biosynthetic process |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| E | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| F | 0000166 | molecular_function | nucleotide binding |
| F | 0009236 | biological_process | cobalamin biosynthetic process |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| F | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| G | 0000166 | molecular_function | nucleotide binding |
| G | 0009236 | biological_process | cobalamin biosynthetic process |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| G | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
| H | 0000166 | molecular_function | nucleotide binding |
| H | 0009236 | biological_process | cobalamin biosynthetic process |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| H | 0102919 | molecular_function | 5,6-dimethylbenzimidazole synthase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FNR B 501 |
| Chain | Residue |
| A | PRO58 |
| B | ASP32 |
| B | ARG34 |
| B | LEU108 |
| B | TRP165 |
| B | VAL166 |
| B | SER167 |
| B | ILE168 |
| B | PRO202 |
| B | LEU204 |
| B | HOH516 |
| A | SER59 |
| A | VAL60 |
| A | PHE62 |
| A | MET140 |
| A | SER144 |
| A | OXY606 |
| B | ARG30 |
| B | ARG31 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FNR A 502 |
| Chain | Residue |
| A | ARG30 |
| A | ARG31 |
| A | ASP32 |
| A | ARG34 |
| A | LEU108 |
| A | TRP165 |
| A | VAL166 |
| A | SER167 |
| A | ILE168 |
| A | PRO202 |
| A | LEU204 |
| A | HOH562 |
| B | PRO58 |
| B | SER59 |
| B | VAL60 |
| B | MET140 |
| B | SER144 |
| B | OXY602 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FNR D 503 |
| Chain | Residue |
| C | PRO58 |
| C | SER59 |
| C | VAL60 |
| C | PHE62 |
| C | MET140 |
| C | SER144 |
| C | OXY605 |
| D | ARG30 |
| D | ARG31 |
| D | ASP32 |
| D | ARG34 |
| D | LEU108 |
| D | TRP165 |
| D | VAL166 |
| D | SER167 |
| D | ILE168 |
| D | PRO202 |
| D | LEU204 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE FNR C 504 |
| Chain | Residue |
| C | ARG30 |
| C | ARG31 |
| C | ASP32 |
| C | ARG34 |
| C | LEU108 |
| C | TRP165 |
| C | VAL166 |
| C | SER167 |
| C | ILE168 |
| C | LEU204 |
| D | PRO58 |
| D | SER59 |
| D | VAL60 |
| D | MET140 |
| D | SER144 |
| D | OXY601 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FNR F 505 |
| Chain | Residue |
| E | PRO58 |
| E | SER59 |
| E | VAL60 |
| E | PHE62 |
| E | MET140 |
| E | SER144 |
| E | OXY607 |
| F | ARG30 |
| F | ARG31 |
| F | ASP32 |
| F | ARG34 |
| F | LYS107 |
| F | LEU108 |
| F | TRP165 |
| F | VAL166 |
| F | SER167 |
| F | ILE168 |
| F | PRO202 |
| F | LEU204 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE FNR E 506 |
| Chain | Residue |
| F | PRO58 |
| F | SER59 |
| F | VAL60 |
| F | PHE62 |
| F | MET140 |
| F | TYR143 |
| F | SER144 |
| F | OXY608 |
| E | ARG30 |
| E | ARG31 |
| E | ASP32 |
| E | ARG34 |
| E | LEU108 |
| E | TRP165 |
| E | VAL166 |
| E | SER167 |
| E | PRO202 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FNR H 507 |
| Chain | Residue |
| G | PRO58 |
| G | SER59 |
| G | VAL60 |
| G | PHE62 |
| G | MET140 |
| G | SER144 |
| G | OXY603 |
| H | ARG30 |
| H | ARG31 |
| H | ASP32 |
| H | ARG34 |
| H | LEU108 |
| H | TRP165 |
| H | VAL166 |
| H | SER167 |
| H | ILE168 |
| H | PRO202 |
| H | LEU204 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE FNR G 508 |
| Chain | Residue |
| G | ARG30 |
| G | ARG31 |
| G | ASP32 |
| G | ARG34 |
| G | LEU108 |
| G | TRP165 |
| G | VAL166 |
| G | SER167 |
| G | PRO202 |
| G | LEU204 |
| G | HOH564 |
| H | PRO58 |
| H | SER59 |
| H | VAL60 |
| H | PHE62 |
| H | MET140 |
| H | SER144 |
| H | OXY604 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXY D 601 |
| Chain | Residue |
| C | FNR504 |
| D | GLY61 |
| D | LEU132 |
| D | GLY133 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OXY B 602 |
| Chain | Residue |
| A | FNR502 |
| B | GLY61 |
| B | LEU132 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXY G 603 |
| Chain | Residue |
| G | GLY61 |
| G | LEU132 |
| G | GLY133 |
| H | FNR507 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OXY H 604 |
| Chain | Residue |
| G | FNR508 |
| H | GLY61 |
| H | LEU132 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OXY C 605 |
| Chain | Residue |
| C | GLY61 |
| C | LEU132 |
| D | FNR503 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXY A 606 |
| Chain | Residue |
| A | GLY61 |
| A | LEU132 |
| A | GLY133 |
| B | FNR501 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OXY E 607 |
| Chain | Residue |
| E | GLY61 |
| E | LEU132 |
| F | FNR505 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE OXY F 608 |
| Chain | Residue |
| E | LEU108 |
| E | FNR506 |
| F | GLY61 |
| F | LEU132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 32 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ARG30 | |
| C | SER59 | |
| C | LEU108 | |
| C | SER167 | |
| D | ARG30 | |
| D | SER59 | |
| D | LEU108 | |
| D | SER167 | |
| E | ARG30 | |
| E | SER59 | |
| E | LEU108 | |
| A | SER59 | |
| E | SER167 | |
| F | ARG30 | |
| F | SER59 | |
| F | LEU108 | |
| F | SER167 | |
| G | ARG30 | |
| G | SER59 | |
| G | LEU108 | |
| G | SER167 | |
| H | ARG30 | |
| A | LEU108 | |
| H | SER59 | |
| H | LEU108 | |
| H | SER167 | |
| A | SER167 | |
| B | ARG30 | |
| B | SER59 | |
| B | LEU108 | |
| B | SER167 | |
| C | ARG30 |
