2ISK

BluB bound to flavin anion (charge transfer complex)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0009236	biological_process	cobalamin biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
B	0000166	molecular_function	nucleotide binding
B	0009236	biological_process	cobalamin biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
B	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
C	0000166	molecular_function	nucleotide binding
C	0009236	biological_process	cobalamin biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
C	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
D	0000166	molecular_function	nucleotide binding
D	0009236	biological_process	cobalamin biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
D	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
E	0000166	molecular_function	nucleotide binding
E	0009236	biological_process	cobalamin biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
E	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
F	0000166	molecular_function	nucleotide binding
F	0009236	biological_process	cobalamin biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
F	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
G	0000166	molecular_function	nucleotide binding
G	0009236	biological_process	cobalamin biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
G	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity
H	0000166	molecular_function	nucleotide binding
H	0009236	biological_process	cobalamin biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0016705	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
H	0102919	molecular_function	5,6-dimethylbenzimidazole synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FNR B 501

Chain	Residue
A	PRO58
B	ARG34
B	LEU108
B	TRP165
B	VAL166
B	SER167
B	ILE168
B	PRO202
B	LEU204
B	HOH543
B	HOH782
A	SER59
B	HOH842
B	HOH1644
A	VAL60
A	PHE62
A	MET140
A	SER144
B	ARG30
B	ARG31
B	ASP32

---

site_id	AC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE FNR A 502

Chain	Residue
A	ARG30
A	ARG31
A	ASP32
A	ARG34
A	LEU108
A	TRP165
A	VAL166
A	SER167
A	ILE168
A	PRO202
A	LEU204
A	HOH512
A	HOH524
A	HOH542
B	PRO58
B	SER59
B	VAL60
B	GLY61
B	MET140
B	SER144

---

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE FNR D 503

Chain	Residue
C	PRO58
C	SER59
C	VAL60
C	PHE62
C	MET140
C	SER144
D	ARG30
D	ARG31
D	ASP32
D	ARG34
D	LEU108
D	TRP165
D	VAL166
D	SER167
D	ILE168
D	PRO202
D	LEU204
D	HOH513
D	HOH536
D	HOH791

---

site_id	AC4
Number of Residues	20
Details	BINDING SITE FOR RESIDUE FNR C 504

Chain	Residue
C	ARG30
C	ARG31
C	ASP32
C	ARG34
C	LEU108
C	TRP165
C	VAL166
C	SER167
C	ILE168
C	PRO202
C	LEU204
C	HOH511
C	HOH577
C	HOH579
C	HOH1090
D	PRO58
D	SER59
D	VAL60
D	MET140
D	SER144

---

site_id	AC5
Number of Residues	22
Details	BINDING SITE FOR RESIDUE FNR F 505

Chain	Residue
F	HOH550
F	HOH671
F	HOH1359
F	HOH1645
E	PRO58
E	SER59
E	VAL60
E	PHE62
E	MET140
E	SER144
F	ARG30
F	ARG31
F	ASP32
F	ARG34
F	LEU108
F	TRP165
F	VAL166
F	SER167
F	ILE168
F	PRO202
F	LEU204
F	HOH529

---

site_id	AC6
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FNR E 506

Chain	Residue
E	ARG30
E	ARG31
E	ASP32
E	ARG34
E	LEU108
E	TRP165
E	VAL166
E	SER167
E	ILE168
E	PRO202
E	LEU204
E	HOH510
E	HOH534
E	HOH662
E	HOH1266
F	PRO58
F	SER59
F	VAL60
F	PHE62
F	MET140
F	SER144

---

site_id	AC7
Number of Residues	21
Details	BINDING SITE FOR RESIDUE FNR H 507

Chain	Residue
G	PRO58
G	SER59
G	VAL60
G	PHE62
G	MET140
G	SER144
H	ARG30
H	ARG31
H	ASP32
H	ARG34
H	LEU108
H	TRP165
H	VAL166
H	SER167
H	ILE168
H	PRO202
H	LEU204
H	HOH509
H	HOH592
H	HOH636
H	HOH642

---

site_id	AC8
Number of Residues	19
Details	BINDING SITE FOR RESIDUE FNR G 508

Chain	Residue
G	ARG30
G	ARG31
G	ASP32
G	ARG34
G	LEU108
G	TRP165
G	VAL166
G	SER167
G	ILE168
G	PRO202
G	LEU204
G	HOH514
G	HOH1144
H	PRO58
H	SER59
H	VAL60
H	GLY61
H	MET140
H	SER144

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	BINDING:

Chain	Residue	Details
A	ARG30
C	SER59
C	LEU108
C	SER167
D	ARG30
D	SER59
D	LEU108
D	SER167
E	ARG30
E	SER59
E	LEU108
A	SER59
E	SER167
F	ARG30
F	SER59
F	LEU108
F	SER167
G	ARG30
G	SER59
G	LEU108
G	SER167
H	ARG30
A	LEU108
H	SER59
H	LEU108
H	SER167
A	SER167
B	ARG30
B	SER59
B	LEU108
B	SER167
C	ARG30

---