2ISA
Crystal Structure of Vibrio salmonicida catalase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004096 | molecular_function | catalase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0020037 | molecular_function | heme binding |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004096 | molecular_function | catalase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0020037 | molecular_function | heme binding |
| B | 0042542 | biological_process | response to hydrogen peroxide |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0098869 | biological_process | cellular oxidant detoxification |
| C | 0004096 | molecular_function | catalase activity |
| C | 0004601 | molecular_function | peroxidase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006979 | biological_process | response to oxidative stress |
| C | 0020037 | molecular_function | heme binding |
| C | 0042542 | biological_process | response to hydrogen peroxide |
| C | 0042597 | cellular_component | periplasmic space |
| C | 0042744 | biological_process | hydrogen peroxide catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0098869 | biological_process | cellular oxidant detoxification |
| D | 0004096 | molecular_function | catalase activity |
| D | 0004601 | molecular_function | peroxidase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006979 | biological_process | response to oxidative stress |
| D | 0020037 | molecular_function | heme binding |
| D | 0042542 | biological_process | response to hydrogen peroxide |
| D | 0042597 | cellular_component | periplasmic space |
| D | 0042744 | biological_process | hydrogen peroxide catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0098869 | biological_process | cellular oxidant detoxification |
| E | 0004096 | molecular_function | catalase activity |
| E | 0004601 | molecular_function | peroxidase activity |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0006979 | biological_process | response to oxidative stress |
| E | 0020037 | molecular_function | heme binding |
| E | 0042542 | biological_process | response to hydrogen peroxide |
| E | 0042597 | cellular_component | periplasmic space |
| E | 0042744 | biological_process | hydrogen peroxide catabolic process |
| E | 0046872 | molecular_function | metal ion binding |
| E | 0098869 | biological_process | cellular oxidant detoxification |
| F | 0004096 | molecular_function | catalase activity |
| F | 0004601 | molecular_function | peroxidase activity |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0006979 | biological_process | response to oxidative stress |
| F | 0020037 | molecular_function | heme binding |
| F | 0042542 | biological_process | response to hydrogen peroxide |
| F | 0042597 | cellular_component | periplasmic space |
| F | 0042744 | biological_process | hydrogen peroxide catabolic process |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0098869 | biological_process | cellular oxidant detoxification |
| G | 0004096 | molecular_function | catalase activity |
| G | 0004601 | molecular_function | peroxidase activity |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0006979 | biological_process | response to oxidative stress |
| G | 0020037 | molecular_function | heme binding |
| G | 0042542 | biological_process | response to hydrogen peroxide |
| G | 0042597 | cellular_component | periplasmic space |
| G | 0042744 | biological_process | hydrogen peroxide catabolic process |
| G | 0046872 | molecular_function | metal ion binding |
| G | 0098869 | biological_process | cellular oxidant detoxification |
| H | 0004096 | molecular_function | catalase activity |
| H | 0004601 | molecular_function | peroxidase activity |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0006979 | biological_process | response to oxidative stress |
| H | 0020037 | molecular_function | heme binding |
| H | 0042542 | biological_process | response to hydrogen peroxide |
| H | 0042597 | cellular_component | periplasmic space |
| H | 0042744 | biological_process | hydrogen peroxide catabolic process |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL D 5485 |
| Chain | Residue |
| A | ARG45 |
| D | ARG45 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 6485 |
| Chain | Residue |
| B | ARG45 |
| C | ARG45 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL H 7485 |
| Chain | Residue |
| E | ARG45 |
| H | ARG45 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL F 8485 |
| Chain | Residue |
| F | ARG45 |
| G | ARG45 |
| H | HOH7859 |
| site_id | AC5 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM A 486 |
| Chain | Residue |
| A | ARG51 |
| A | OMT53 |
| A | HIS54 |
| A | ARG91 |
| A | GLY110 |
| A | ALA125 |
| A | GLY126 |
| A | ASN127 |
| A | PRO137 |
| A | PHE140 |
| A | GLY195 |
| A | SER196 |
| A | HIS197 |
| A | LEU278 |
| A | PHE313 |
| A | MET329 |
| A | ARG333 |
| A | TYR337 |
| A | GLN341 |
| A | ARG344 |
| A | HOH5515 |
| A | HOH5524 |
| A | HOH5526 |
| A | HOH5671 |
| B | LEU40 |
| B | ASP44 |
| site_id | AC6 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM B 486 |
| Chain | Residue |
| A | LEU40 |
| A | ASP44 |
| B | ARG51 |
| B | HIS54 |
| B | ARG91 |
| B | GLY110 |
| B | ALA125 |
| B | GLY126 |
| B | ASN127 |
| B | PRO137 |
| B | PHE140 |
| B | GLY195 |
| B | SER196 |
| B | HIS197 |
| B | LEU278 |
| B | PHE313 |
| B | MET329 |
| B | ARG333 |
| B | TYR337 |
| B | ALA340 |
| B | GLN341 |
| B | ARG344 |
| B | HOH6500 |
| B | HOH6502 |
| B | HOH6584 |
| site_id | AC7 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM C 485 |
| Chain | Residue |
| C | ARG51 |
| C | OMT53 |
| C | HIS54 |
| C | ARG91 |
| C | GLY110 |
| C | SER112 |
| C | ALA125 |
| C | GLY126 |
| C | ASN127 |
| C | PRO137 |
| C | PHE140 |
| C | GLY195 |
| C | SER196 |
| C | HIS197 |
| C | LEU278 |
| C | PHE313 |
| C | MET329 |
| C | ARG333 |
| C | TYR337 |
| C | GLN341 |
| C | ARG344 |
| C | HOH5502 |
| C | HOH5527 |
| C | HOH5532 |
| D | LEU40 |
| D | ASP44 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM D 485 |
| Chain | Residue |
| D | LEU278 |
| D | PHE313 |
| D | MET329 |
| D | ARG333 |
| D | ALA336 |
| D | TYR337 |
| D | ALA340 |
| D | GLN341 |
| D | ARG344 |
| D | HOH5517 |
| D | HOH5545 |
| D | HOH5589 |
| C | ASP44 |
| D | ARG51 |
| D | HIS54 |
| D | ARG91 |
| D | GLY110 |
| D | ALA125 |
| D | GLY126 |
| D | ASN127 |
| D | PRO137 |
| D | PHE140 |
| D | GLY195 |
| D | SER196 |
| D | HIS197 |
| site_id | AC9 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM E 486 |
| Chain | Residue |
| E | ARG51 |
| E | OMT53 |
| E | HIS54 |
| E | ARG91 |
| E | GLY110 |
| E | SER112 |
| E | ALA125 |
| E | GLY126 |
| E | ASN127 |
| E | PRO137 |
| E | PHE140 |
| E | GLY195 |
| E | SER196 |
| E | HIS197 |
| E | PHE313 |
| E | MET329 |
| E | ARG333 |
| E | TYR337 |
| E | ALA340 |
| E | GLN341 |
| E | ARG344 |
| E | HOH5513 |
| E | HOH5521 |
| E | HOH5602 |
| F | LEU40 |
| F | ASP44 |
| site_id | BC1 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM F 486 |
| Chain | Residue |
| E | LEU40 |
| E | ASP44 |
| F | ARG51 |
| F | OMT53 |
| F | HIS54 |
| F | ARG91 |
| F | GLY110 |
| F | SER112 |
| F | ALA125 |
| F | GLY126 |
| F | ASN127 |
| F | PRO137 |
| F | PHE140 |
| F | GLY195 |
| F | SER196 |
| F | HIS197 |
| F | LEU278 |
| F | PHE313 |
| F | MET329 |
| F | ARG333 |
| F | TYR337 |
| F | GLN341 |
| F | ARG344 |
| F | HOH8509 |
| F | HOH8527 |
| F | HOH8570 |
| site_id | BC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE HEM G 485 |
| Chain | Residue |
| G | ARG51 |
| G | HIS54 |
| G | ARG91 |
| G | GLY110 |
| G | SER112 |
| G | ALA125 |
| G | GLY126 |
| G | ASN127 |
| G | PRO137 |
| G | PHE140 |
| G | GLY195 |
| G | SER196 |
| G | HIS197 |
| G | LEU278 |
| G | PHE313 |
| G | MET329 |
| G | ARG333 |
| G | TYR337 |
| G | GLN341 |
| G | ARG344 |
| G | HOH5510 |
| G | HOH5517 |
| G | HOH5566 |
| H | LEU40 |
| H | ASP44 |
| site_id | BC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE HEM H 485 |
| Chain | Residue |
| G | ASP44 |
| H | ARG51 |
| H | OMT53 |
| H | HIS54 |
| H | ARG91 |
| H | GLY110 |
| H | SER112 |
| H | ALA125 |
| H | GLY126 |
| H | ASN127 |
| H | PRO137 |
| H | PHE140 |
| H | GLY195 |
| H | SER196 |
| H | HIS197 |
| H | LEU278 |
| H | PHE313 |
| H | MET329 |
| H | ARG333 |
| H | TYR337 |
| H | GLN341 |
| H | ARG344 |
| H | HOH7501 |
| H | HOH7567 |
| H | HOH7628 |
| H | HOH7891 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL C 5487 |
| Chain | Residue |
| A | VAL34 |
| A | LEU37 |
| A | HOH5753 |
| C | ASN314 |
| C | ALA316 |
| C | LEU334 |
| C | PHE335 |
| C | GLY338 |
| C | ASP339 |
| C | ARG342 |
| C | HOH5770 |
| site_id | BC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL D 5488 |
| Chain | Residue |
| B | VAL34 |
| B | LEU37 |
| B | HOH6802 |
| D | ASN314 |
| D | ALA316 |
| D | PHE335 |
| D | GLY338 |
| D | ASP339 |
| D | ARG342 |
| D | HOH5688 |
| site_id | BC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 5489 |
| Chain | Residue |
| A | ASN314 |
| A | ALA316 |
| A | LEU334 |
| A | PHE335 |
| A | GLY338 |
| A | ASP339 |
| A | ARG342 |
| C | VAL34 |
| C | LEU37 |
| C | HOH5755 |
| C | HOH5889 |
| site_id | BC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 5490 |
| Chain | Residue |
| B | ASN314 |
| B | ALA316 |
| B | LEU334 |
| B | PHE335 |
| B | GLY338 |
| B | ASP339 |
| B | ARG342 |
| B | HOH6828 |
| B | HOH6941 |
| D | VAL34 |
| site_id | BC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL G 5491 |
| Chain | Residue |
| E | VAL34 |
| E | LEU37 |
| E | HOH5768 |
| G | ASN314 |
| G | ALA316 |
| G | LEU334 |
| G | PHE335 |
| G | GLY338 |
| G | ASP339 |
| G | ARG342 |
| G | HOH5693 |
| site_id | BC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL H 5492 |
| Chain | Residue |
| F | VAL34 |
| H | ASN314 |
| H | ALA316 |
| H | LEU334 |
| H | PHE335 |
| H | GLY338 |
| H | ASP339 |
| H | ARG342 |
| H | HOH7721 |
| H | HOH7757 |
| site_id | CC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL E 5493 |
| Chain | Residue |
| E | ASN314 |
| E | ALA316 |
| E | LEU334 |
| E | PHE335 |
| E | GLY338 |
| E | ASP339 |
| E | ARG342 |
| E | HOH5730 |
| E | HOH5955 |
| G | VAL34 |
| G | LEU37 |
| site_id | CC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL F 5494 |
| Chain | Residue |
| F | ASN314 |
| F | ALA316 |
| F | LEU334 |
| F | PHE335 |
| F | GLY338 |
| F | ASP339 |
| F | ARG342 |
| F | HOH8652 |
| F | HOH8704 |
| H | VAL34 |
| H | LEU37 |
Functional Information from PROSITE/UniProt
