2IRY
Crystal Structure of the Polymerase Domain from Mycobacterium tuberculosis Ligase D with dGTP and Manganese.
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MN A 1100 |
Chain | Residue |
A | ASP140 |
A | ASP142 |
A | DGT1102 |
A | HOH1397 |
A | HOH1412 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MN B 1101 |
Chain | Residue |
B | HOH1394 |
B | ASP140 |
B | ASP142 |
B | DGT1103 |
B | HOH1387 |
site_id | AC3 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE DGT A 1102 |
Chain | Residue |
A | PHE67 |
A | LYS69 |
A | ASP140 |
A | ASP142 |
A | SER175 |
A | SER177 |
A | LYS178 |
A | GLY179 |
A | HIS181 |
A | GLN233 |
A | THR239 |
A | ARG247 |
A | MN1100 |
A | HOH1396 |
A | HOH1397 |
A | HOH1400 |
A | HOH1401 |
A | HOH1404 |
A | HOH1412 |
A | HOH1420 |
A | HOH1426 |
site_id | AC4 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE DGT B 1103 |
Chain | Residue |
B | ASP140 |
B | ASP142 |
B | SER175 |
B | SER177 |
B | LYS178 |
B | GLY179 |
B | HIS181 |
B | ILE241 |
B | ARG247 |
B | MN1101 |
B | HOH1387 |
B | HOH1391 |
B | HOH1394 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 62 |
Details | DNA_BIND: Interaction with target DNA |
Chain | Residue | Details |
A | ASN16-LYS19 | |
A | ASP230-LYS238 | |
B | ASN16-LYS19 | |
B | LYS29 | |
B | ARG56-PRO58 | |
B | PHE66-GLN70 | |
B | SER74 | |
B | HIS86-THR91 | |
B | GLN107 | |
B | ASP140 | |
B | MET218-ARG223 | |
A | LYS29 | |
B | ASP230-LYS238 | |
A | ARG56-PRO58 | |
A | PHE66-GLN70 | |
A | SER74 | |
A | HIS86-THR91 | |
A | GLN107 | |
A | ASP140 | |
A | MET218-ARG223 |
site_id | SWS_FT_FI2 |
Number of Residues | 18 |
Details | BINDING: BINDING => ECO:0000269|PubMed:17174332 |
Chain | Residue | Details |
A | LYS55 | |
B | LYS55 | |
B | HIS114 | |
B | ASP140 | |
B | ASP142 | |
B | SER175 | |
B | ASP230 | |
B | GLN233 | |
B | THR239 | |
B | ARG247 | |
A | HIS114 | |
A | ASP140 | |
A | ASP142 | |
A | SER175 | |
A | ASP230 | |
A | GLN233 | |
A | THR239 | |
A | ARG247 |