2IRX
Crystal Structure of the Polymerase Domain from Mycobacterium tuberculosis Ligase D with GTP and Manganese.
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 304 |
| Chain | Residue |
| A | ASP140 |
| A | ASP142 |
| A | GTP305 |
| A | HOH583 |
| A | HOH584 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE GTP A 305 |
| Chain | Residue |
| A | ASP142 |
| A | SER175 |
| A | SER177 |
| A | LYS178 |
| A | GLY179 |
| A | HIS181 |
| A | GLN233 |
| A | THR239 |
| A | ARG247 |
| A | ARG249 |
| A | MN304 |
| A | HOH431 |
| A | HOH475 |
| A | HOH481 |
| A | HOH580 |
| A | HOH581 |
| A | HOH582 |
| A | HOH584 |
| A | HOH585 |
| A | HOH586 |
| A | HOH591 |
| A | HOH593 |
| A | HOH597 |
| A | HOH617 |
| A | LYS55 |
| A | PHE67 |
| A | HIS114 |
| A | ASP140 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 31 |
| Details | DNA binding: {"description":"Interaction with target DNA"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 252 |
| Details | Region: {"description":"DNA repair polymerase domain (Pol); interacts with Ku"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17174332","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
