2IPX
Human Fibrillarin
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 317 |
| Chain | Residue |
| A | PHE141 |
| A | THR209 |
| A | GLU304 |
| A | HOH4005 |
| A | HOH4006 |
| A | HOH4027 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 318 |
| Chain | Residue |
| A | HOH4101 |
| A | GLN289 |
| A | GLU290 |
| A | GLU290 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE MTA A 4001 |
| Chain | Residue |
| A | GLY168 |
| A | ALA170 |
| A | GLU192 |
| A | PHE193 |
| A | GLU216 |
| A | ASP217 |
| A | ALA218 |
| A | ARG219 |
| A | ASP237 |
| A | VAL238 |
| A | GLN240 |
| A | HOH4112 |
| A | HOH4216 |
| A | HOH4234 |
Functional Information from PROSITE/UniProt
| site_id | PS00566 |
| Number of Residues | 15 |
| Details | FIBRILLARIN Fibrillarin signature. GLVYAVEFShRsgRD |
| Chain | Residue | Details |
| A | GLY186-ASP200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9Y9U3","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"The crystal structure of human fibrillarin in complex with SAH.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"30540930","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
