2IPA
solution structure of Trx-ArsC complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0015035 | molecular_function | protein-disulfide reductase activity |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0030612 | molecular_function | arsenate reductase (thioredoxin) activity |
| B | 0046685 | biological_process | response to arsenic-containing substance |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 102 |
| Details | Domain: {"description":"Thioredoxin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00691","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_01624","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11698660","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1cqg |
| Chain | Residue | Details |
| A | SER32 | |
| A | CYS29 |
