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2IOP

Crystal Structure of Full-length HtpG, the Escherichia coli Hsp90, Bound to ADP

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006457biological_processprotein folding
A0006974biological_processDNA damage response
A0009408biological_processresponse to heat
A0016887molecular_functionATP hydrolysis activity
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043093biological_processFtsZ-dependent cytokinesis
A0044183molecular_functionprotein folding chaperone
A0051082molecular_functionunfolded protein binding
A0051087molecular_functionprotein-folding chaperone binding
A0140662molecular_functionATP-dependent protein folding chaperone
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006457biological_processprotein folding
B0006974biological_processDNA damage response
B0009408biological_processresponse to heat
B0016887molecular_functionATP hydrolysis activity
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043093biological_processFtsZ-dependent cytokinesis
B0044183molecular_functionprotein folding chaperone
B0051082molecular_functionunfolded protein binding
B0051087molecular_functionprotein-folding chaperone binding
B0140662molecular_functionATP-dependent protein folding chaperone
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006457biological_processprotein folding
C0006974biological_processDNA damage response
C0009408biological_processresponse to heat
C0016887molecular_functionATP hydrolysis activity
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043093biological_processFtsZ-dependent cytokinesis
C0044183molecular_functionprotein folding chaperone
C0051082molecular_functionunfolded protein binding
C0051087molecular_functionprotein-folding chaperone binding
C0140662molecular_functionATP-dependent protein folding chaperone
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006457biological_processprotein folding
D0006974biological_processDNA damage response
D0009408biological_processresponse to heat
D0016887molecular_functionATP hydrolysis activity
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043093biological_processFtsZ-dependent cytokinesis
D0044183molecular_functionprotein folding chaperone
D0051082molecular_functionunfolded protein binding
D0051087molecular_functionprotein-folding chaperone binding
D0140662molecular_functionATP-dependent protein folding chaperone
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE ADP A 1001
ChainResidue
AASN38
AASP80
AMET85
AHIS93
AILE97
AALA98
AGLY126
APHE127
ATHR174

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE ADP B 1002
ChainResidue
BASN38
BASP80
BMET85
BHIS93
BILE97
BALA98
BGLY126
BPHE127
BTHR174

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE ADP C 1003
ChainResidue
CASN38
CASP80
CMET85
CHIS93
CILE97
CALA98
CGLY126
CPHE127
CTHR174

site_idAC4
Number of Residues10
DetailsBINDING SITE FOR RESIDUE ADP D 1004
ChainResidue
DASN38
DASP80
DMET85
DHIS93
DTHR96
DILE97
DALA98
DGLY126
DPHE127
DTHR174

Functional Information from PROSITE/UniProt
site_idPS00298
Number of Residues10
DetailsHSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE
ChainResidueDetails
ATYR25-GLU34

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues20
DetailsBINDING: BINDING => ECO:0000269|PubMed:15837196
ChainResidueDetails
AASN38
AASP80
DASP80
DPHE127
DTHR174
DHIS255
APHE127
ATHR174
AHIS255
BASN38
BASP80
BPHE127
BTHR174
BHIS255
CASN38
CASP80
CPHE127
CTHR174
CHIS255
DASN38

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PDB entries from 2024-06-12

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