Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0008216 | biological_process | spermidine metabolic process |
| A | 0008884 | molecular_function | glutathionylspermidine amidase activity |
| A | 0008885 | molecular_function | glutathionylspermidine synthase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0008216 | biological_process | spermidine metabolic process |
| B | 0008884 | molecular_function | glutathionylspermidine amidase activity |
| B | 0008885 | molecular_function | glutathionylspermidine synthase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 5001 |
| Chain | Residue |
| A | GLU330 |
| A | ASN332 |
| A | GLY537 |
| A | ANP964 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 5002 |
| Chain | Residue |
| A | ASP318 |
| A | GLU330 |
| A | ANP964 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 5003 |
| Chain | Residue |
| B | ANP965 |
| B | GLU330 |
| B | ASN332 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG B 5004 |
| Chain | Residue |
| B | ASP318 |
| B | GLU330 |
| B | ANP965 |
| site_id | AC5 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE ANP A 964 |
| Chain | Residue |
| A | ARG316 |
| A | ASP318 |
| A | TYR329 |
| A | GLU330 |
| A | ASN332 |
| A | LYS498 |
| A | ALA531 |
| A | LYS533 |
| A | GLY537 |
| A | ARG538 |
| A | CYS539 |
| A | GLY540 |
| A | GLN568 |
| A | GLN569 |
| A | LEU570 |
| A | TRP571 |
| A | LEU573 |
| A | GLN582 |
| A | LEU603 |
| A | VAL604 |
| A | ILE605 |
| A | MG5001 |
| A | MG5002 |
| A | HOH5026 |
| A | HOH5036 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE ANP B 965 |
| Chain | Residue |
| B | ARG316 |
| B | ASP318 |
| B | TYR329 |
| B | GLU330 |
| B | ASN332 |
| B | LYS498 |
| B | ALA531 |
| B | LYS533 |
| B | GLY537 |
| B | ARG538 |
| B | CYS539 |
| B | GLY540 |
| B | GLN568 |
| B | GLN569 |
| B | LEU570 |
| B | TRP571 |
| B | LEU573 |
| B | GLN582 |
| B | LEU603 |
| B | VAL604 |
| B | ILE605 |
| B | MG5003 |
| B | MG5004 |
| B | HOH5199 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 18 |
| Details | Region: {"description":"Linker"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"S-(gamma-glutamyl-cysteinyl-glycyl)-cysteine intermediate","evidences":[{"source":"PubMed","id":"9398217","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 52 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Increases nucleophilicity of active site Cys; for amidase activity"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer; for synthetase activity"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Cysteine sulfenic acid (-SOH); transient","evidences":[{"source":"PubMed","id":"20530482","evidenceCode":"ECO:0000269"}]} |
