2INF

Crystal Structure of Uroporphyrinogen Decarboxylase from Bacillus subtilis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004853	molecular_function	uroporphyrinogen decarboxylase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006778	biological_process	porphyrin-containing compound metabolic process
A	0006779	biological_process	porphyrin-containing compound biosynthetic process
A	0006782	biological_process	protoporphyrinogen IX biosynthetic process
A	0006783	biological_process	heme biosynthetic process
A	0016831	molecular_function	carboxy-lyase activity
B	0004853	molecular_function	uroporphyrinogen decarboxylase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006778	biological_process	porphyrin-containing compound metabolic process
B	0006779	biological_process	porphyrin-containing compound biosynthetic process
B	0006782	biological_process	protoporphyrinogen IX biosynthetic process
B	0006783	biological_process	heme biosynthetic process
B	0016831	molecular_function	carboxy-lyase activity
C	0004853	molecular_function	uroporphyrinogen decarboxylase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006778	biological_process	porphyrin-containing compound metabolic process
C	0006779	biological_process	porphyrin-containing compound biosynthetic process
C	0006782	biological_process	protoporphyrinogen IX biosynthetic process
C	0006783	biological_process	heme biosynthetic process
C	0016831	molecular_function	carboxy-lyase activity
D	0004853	molecular_function	uroporphyrinogen decarboxylase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006778	biological_process	porphyrin-containing compound metabolic process
D	0006779	biological_process	porphyrin-containing compound biosynthetic process
D	0006782	biological_process	protoporphyrinogen IX biosynthetic process
D	0006783	biological_process	heme biosynthetic process
D	0016831	molecular_function	carboxy-lyase activity

Functional Information from PROSITE/UniProt

site_id	PS00906
Number of Residues	10
Details	UROD_1 Uroporphyrinogen decarboxylase signature 1. PVWYMRQAGR

Chain	Residue	Details
A	PRO24-ARG33

---

site_id	PS00907
Number of Residues	17
Details	UROD_2 Uroporphyrinogen decarboxylase signature 2. IGFSGaPFTLasYmt.EG

Chain	Residue	Details
A	ILE142-GLY158

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG29
B	TYR154
B	SER209
B	HIS322
C	ARG29
C	PHE48
C	ASP78
C	TYR154
C	SER209
C	HIS322
D	ARG29
A	PHE48
D	PHE48
D	ASP78
D	TYR154
D	SER209
D	HIS322
A	ASP78
A	TYR154
A	SER209
A	HIS322
B	ARG29
B	PHE48
B	ASP78

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	SITE: Transition state stabilizer => ECO:0000250

Chain	Residue	Details
A	ASP78
B	ASP78
C	ASP78
D	ASP78

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1uro

Chain	Residue	Details
A	TYR154
A	ASP78

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1uro

Chain	Residue	Details
B	TYR154
B	ASP78

---

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1uro

Chain	Residue	Details
C	TYR154
C	ASP78

---

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1uro

Chain	Residue	Details
D	TYR154
D	ASP78

---