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2IMI

Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0004364molecular_functionglutathione transferase activity
A0006749biological_processglutathione metabolic process
B0003824molecular_functioncatalytic activity
B0004364molecular_functionglutathione transferase activity
B0006749biological_processglutathione metabolic process
Functional Information from PDB Data
site_idAC1
Number of Residues20
DetailsBINDING SITE FOR RESIDUE GSH A 224
ChainResidue
ASER12
ASER68
APHE108
AARG112
AHOH229
AHOH250
AHOH259
AHOH291
AHOH357
AHOH366
AHOH392
APRO14
AHOH422
ALEU36
AHIS41
AHIS53
ATHR54
AILE55
APRO56
AGLU67

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE GSH B 226
ChainResidue
BSER12
BPRO14
BLEU36
BHIS41
BHIS53
BTHR54
BILE55
BPRO56
BGLU67
BSER68
BPHE108
BARG112
BHOH236
BHOH239
BHOH303
BHOH307
BHOH347
BHOH412

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
ATHR8

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
BTHR8

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PDB entries from 2024-11-13

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