Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2IIR

Acetate kinase from a hypothermophile Thermotoga maritima

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006082	biological_process	organic acid metabolic process
A	0006083	biological_process	acetate metabolic process
A	0006085	biological_process	acetyl-CoA biosynthetic process
A	0008776	molecular_function	acetate kinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016740	molecular_function	transferase activity
A	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
A	0046872	molecular_function	metal ion binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006082	biological_process	organic acid metabolic process
B	0006083	biological_process	acetate metabolic process
B	0006085	biological_process	acetyl-CoA biosynthetic process
B	0008776	molecular_function	acetate kinase activity
B	0016301	molecular_function	kinase activity
B	0016310	biological_process	phosphorylation
B	0016740	molecular_function	transferase activity
B	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
B	0046872	molecular_function	metal ion binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006082	biological_process	organic acid metabolic process
C	0006083	biological_process	acetate metabolic process
C	0006085	biological_process	acetyl-CoA biosynthetic process
C	0008776	molecular_function	acetate kinase activity
C	0016301	molecular_function	kinase activity
C	0016310	biological_process	phosphorylation
C	0016740	molecular_function	transferase activity
C	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
C	0046872	molecular_function	metal ion binding
D	0000166	molecular_function	nucleotide binding
D	0000287	molecular_function	magnesium ion binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006082	biological_process	organic acid metabolic process
D	0006083	biological_process	acetate metabolic process
D	0006085	biological_process	acetyl-CoA biosynthetic process
D	0008776	molecular_function	acetate kinase activity
D	0016301	molecular_function	kinase activity
D	0016310	biological_process	phosphorylation
D	0016740	molecular_function	transferase activity
D	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
D	0046872	molecular_function	metal ion binding
E	0000166	molecular_function	nucleotide binding
E	0000287	molecular_function	magnesium ion binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006082	biological_process	organic acid metabolic process
E	0006083	biological_process	acetate metabolic process
E	0006085	biological_process	acetyl-CoA biosynthetic process
E	0008776	molecular_function	acetate kinase activity
E	0016301	molecular_function	kinase activity
E	0016310	biological_process	phosphorylation
E	0016740	molecular_function	transferase activity
E	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
E	0046872	molecular_function	metal ion binding
F	0000166	molecular_function	nucleotide binding
F	0000287	molecular_function	magnesium ion binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006082	biological_process	organic acid metabolic process
F	0006083	biological_process	acetate metabolic process
F	0006085	biological_process	acetyl-CoA biosynthetic process
F	0008776	molecular_function	acetate kinase activity
F	0016301	molecular_function	kinase activity
F	0016310	biological_process	phosphorylation
F	0016740	molecular_function	transferase activity
F	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
F	0046872	molecular_function	metal ion binding
G	0000166	molecular_function	nucleotide binding
G	0000287	molecular_function	magnesium ion binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0006082	biological_process	organic acid metabolic process
G	0006083	biological_process	acetate metabolic process
G	0006085	biological_process	acetyl-CoA biosynthetic process
G	0008776	molecular_function	acetate kinase activity
G	0016301	molecular_function	kinase activity
G	0016310	biological_process	phosphorylation
G	0016740	molecular_function	transferase activity
G	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
G	0046872	molecular_function	metal ion binding
H	0000166	molecular_function	nucleotide binding
H	0000287	molecular_function	magnesium ion binding
H	0005524	molecular_function	ATP binding
H	0005737	cellular_component	cytoplasm
H	0006082	biological_process	organic acid metabolic process
H	0006083	biological_process	acetate metabolic process
H	0006085	biological_process	acetyl-CoA biosynthetic process
H	0008776	molecular_function	acetate kinase activity
H	0016301	molecular_function	kinase activity
H	0016310	biological_process	phosphorylation
H	0016740	molecular_function	transferase activity
H	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
H	0046872	molecular_function	metal ion binding
I	0000166	molecular_function	nucleotide binding
I	0000287	molecular_function	magnesium ion binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0006082	biological_process	organic acid metabolic process
I	0006083	biological_process	acetate metabolic process
I	0006085	biological_process	acetyl-CoA biosynthetic process
I	0008776	molecular_function	acetate kinase activity
I	0016301	molecular_function	kinase activity
I	0016310	biological_process	phosphorylation
I	0016740	molecular_function	transferase activity
I	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
I	0046872	molecular_function	metal ion binding
J	0000166	molecular_function	nucleotide binding
J	0000287	molecular_function	magnesium ion binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0006082	biological_process	organic acid metabolic process
J	0006083	biological_process	acetate metabolic process
J	0006085	biological_process	acetyl-CoA biosynthetic process
J	0008776	molecular_function	acetate kinase activity
J	0016301	molecular_function	kinase activity
J	0016310	biological_process	phosphorylation
J	0016740	molecular_function	transferase activity
J	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
J	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS01075
Number of Residues	12
Details	ACETATE_KINASE_1 Acetate and butyrate kinases family signature 1. VLvINsGSSSiK

Chain	Residue	Details
A	VAL3-LYS14

site_id	PS01076
Number of Residues	18
Details	ACETATE_KINASE_2 Acetate and butyrate kinases family signature 2. IItcHiGnGaSVaAvkyG

Chain	Residue	Details
A	ILE203-GLY220

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00020","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	140
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00020","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	20
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_00020","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
A	ARG90
A	SER10
A	GLY211
A	ASP147
A	ARG240

site_id	CSA10
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
J	ARG90
J	SER10
J	GLY211
J	ASP147
J	ARG240

site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
B	ARG90
B	SER10
B	GLY211
B	ASP147
B	ARG240

site_id	CSA3
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
C	ARG90
C	SER10
C	GLY211
C	ASP147
C	ARG240

site_id	CSA4
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
D	ARG90
D	SER10
D	GLY211
D	ASP147
D	ARG240

site_id	CSA5
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
E	ARG90
E	SER10
E	GLY211
E	ASP147
E	ARG240

site_id	CSA6
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
F	ARG90
F	SER10
F	GLY211
F	ASP147
F	ARG240

site_id	CSA7
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
G	ARG90
G	SER10
G	GLY211
G	ASP147
G	ARG240

site_id	CSA8
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
H	ARG90
H	SER10
H	GLY211
H	ASP147
H	ARG240

site_id	CSA9
Number of Residues	5
Details	Annotated By Reference To The Literature 1g99

Chain	Residue	Details
I	ARG90
I	SER10
I	GLY211
I	ASP147
I	ARG240

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)