Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0070007 | molecular_function | glutamic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0070007 | molecular_function | glutamic-type endopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY A 398 |
| Chain | Residue |
| A | VAL2 |
| A | GLU3 |
| A | ASN5 |
| B | VAL2 |
| B | GLU3 |
| D | AAR507 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 416 |
| Chain | Residue |
| A | VAL74 |
| A | GLU121 |
| A | GLU69 |
| A | TRP70 |
| A | GLU73 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 397 |
| Chain | Residue |
| A | GLN48 |
| B | ASN188 |
| B | ASP190 |
| B | HOH322 |
| B | HOH371 |
| B | HOH403 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACY B 400 |
| site_id | AC5 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR CHAIN C OF HEPTAPEPTIDE |
| Chain | Residue |
| A | ASN5 |
| A | TRP6 |
| A | THR37 |
| A | GLY44 |
| A | ASP45 |
| A | GLN53 |
| A | ASP57 |
| A | TYR59 |
| A | ASP65 |
| A | TRP67 |
| A | GLU69 |
| A | TYR71 |
| A | PRO72 |
| A | VAL74 |
| A | SER75 |
| A | ASP77 |
| A | GLU136 |
| A | PHE138 |
| A | GLU139 |
| A | GLU140 |
| A | CYS141 |
| A | ASN142 |
| A | SER143 |
| A | THR182 |
| A | HOH329 |
| B | GLU3 |
| B | ASP45 |
| B | GLN48 |
| B | ILE185 |
| C | HOH337 |
| C | HOH408 |
| C | HOH412 |
| C | HOH413 |
| D | AAR507 |
| site_id | AC6 |
| Number of Residues | 31 |
| Details | BINDING SITE FOR CHAIN D OF HEPTAPEPTIDE |
| Chain | Residue |
| A | GLU3 |
| A | ASP45 |
| A | GLN48 |
| A | ACY398 |
| B | ASN5 |
| B | TRP6 |
| B | THR37 |
| B | GLY44 |
| B | ASP45 |
| B | GLN48 |
| B | GLN53 |
| B | ASP57 |
| B | TYR59 |
| B | ASP65 |
| B | TRP67 |
| B | GLU69 |
| B | TYR71 |
| B | PRO72 |
| B | VAL74 |
| B | SER75 |
| B | ASP77 |
| B | GLU136 |
| B | PHE138 |
| B | GLU139 |
| B | GLU140 |
| B | CYS141 |
| B | ASN142 |
| B | SER143 |
| B | THR182 |
| B | HOH392 |
| C | AAR507 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"14993599","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1s2k |
| Chain | Residue | Details |
| A | GLU136 | |
| A | GLN53 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1s2k |
| Chain | Residue | Details |
| B | GLU136 | |
| B | GLN53 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 595 |
| Chain | Residue | Details |
| A | GLN53 | electrostatic stabiliser |
| A | GLU136 | proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 595 |
| Chain | Residue | Details |
| B | GLN53 | electrostatic stabiliser |
| B | GLU136 | proton acceptor, proton donor |
