Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006260 | biological_process | DNA replication |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| B | 0006260 | biological_process | DNA replication |
| B | 0071897 | biological_process | DNA biosynthetic process |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| C | 0006260 | biological_process | DNA replication |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0006260 | biological_process | DNA replication |
| D | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 1001 |
| Chain | Residue |
| A | ASP12 |
| A | TMP2001 |
| A | HOH2003 |
| A | HOH2016 |
| A | HOH2081 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 1002 |
| Chain | Residue |
| A | HOH2017 |
| A | ASP12 |
| A | GLU14 |
| A | ASP167 |
| A | TMP2001 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 1003 |
| Chain | Residue |
| C | ASP12 |
| C | GLU14 |
| C | ASP167 |
| C | TMP2002 |
| C | HOH2008 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 1004 |
| Chain | Residue |
| C | ASP12 |
| C | TMP2002 |
| C | HOH2003 |
| C | HOH2089 |
| C | HOH2090 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN C 1005 |
| Chain | Residue |
| C | HIS162 |
| C | HOH2149 |
| C | HOH2150 |
| C | HOH2151 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TMP A 2001 |
| Chain | Residue |
| A | ASP12 |
| A | THR13 |
| A | GLU14 |
| A | THR15 |
| A | MET18 |
| A | GLU61 |
| A | HIS66 |
| A | PHE102 |
| A | ASP167 |
| A | MN1001 |
| A | MN1002 |
| A | HOH2017 |
| A | HOH2051 |
| A | HOH2074 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE TMP C 2002 |
| Chain | Residue |
| C | ASP12 |
| C | THR13 |
| C | GLU14 |
| C | THR15 |
| C | GLU61 |
| C | HIS66 |
| C | PHE102 |
| C | ASP167 |
| C | EDO1000 |
| C | MN1003 |
| C | MN1004 |
| C | HOH2008 |
| C | HOH2027 |
| C | HOH2044 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1000 |
| Chain | Residue |
| C | HIS98 |
| C | TMP2002 |
| C | HOH2019 |
| C | HOH2038 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 754 |
| Chain | Residue | Details |
| A | ASP12 | metal ligand |
| A | GLU14 | hydrogen bond acceptor, metal ligand, proton acceptor, proton donor |
| A | GLU61 | electrostatic stabiliser, increase basicity, polar interaction |
| A | HIS162 | proton acceptor, proton donor |
| A | ASP167 | metal ligand |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 754 |
| Chain | Residue | Details |
| C | ASP12 | metal ligand |
| C | GLU14 | hydrogen bond acceptor, metal ligand, proton acceptor, proton donor |
| C | GLU61 | electrostatic stabiliser, increase basicity, polar interaction |
| C | HIS162 | proton acceptor, proton donor |
| C | ASP167 | metal ligand |
