Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0006956 | biological_process | complement activation |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU483-CYS488 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SPckGESGGAVF |
| Chain | Residue | Details |
| A | SER653-PHE664 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | PHE489 | |
| A | ALA543 | |
| A | GLY661 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | SER244 | |
| A | SER246 | |
| A | THR319 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | SER272 | |
| Chain | Residue | Details |
| A | THR315 | |
| Chain | Residue | Details |
| A | SER449 | |
| A | SER603 | |
| Chain | Residue | Details |
| A | SER453 | |
| Chain | Residue | Details |
| A | THR633 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | ASP541 | |
| A | HIS487 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER659 | |
| A | GLY660 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY657 | |
| A | SER659 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER659 | |
| A | ASP541 | |
| A | HIS487 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | SER659 | |
| A | ASP541 | |
| A | HIS487 | |
| A | GLY660 | |
| site_id | CSA6 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY657 | |
| A | ASP525 | |
| A | SER659 | |
| A | HIS487 | |
| A | SER678 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY657 | |
| A | ASP525 | |
| A | SER659 | |
| A | HIS487 | |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1a0j |
| Chain | Residue | Details |
| A | GLY657 | |
| A | SER659 | |
| A | ASP541 | |
| A | HIS487 | |
