2I1P

Solution structure of the twelfth cysteine-rich ligand-binding repeat in rat megalin

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 1230

Chain	Residue
A	TYR1206
A	ASP1209
A	VAL1211
A	ASP1213
A	ASP1219
A	GLU1220

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Functional Information from PROSITE/UniProt

site_id	PS01209
Number of Residues	23
Details	LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CInsryr.CDgvyDCrdn.SDEag...C

Chain	Residue	Details
A	CYS1201-CYS1223

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	37
Details	Domain: {"description":"LDL-receptor class A 12","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17245526","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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