2I0F
Lumazine synthase RibH1 from Brucella abortus (Gene BruAb1_0785, Swiss-Prot entry Q57DY1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0009349 | cellular_component | riboflavin synthase complex |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0009349 | cellular_component | riboflavin synthase complex |
| B | 0016740 | molecular_function | transferase activity |
| C | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0009349 | cellular_component | riboflavin synthase complex |
| C | 0016740 | molecular_function | transferase activity |
| D | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0009349 | cellular_component | riboflavin synthase complex |
| D | 0016740 | molecular_function | transferase activity |
| E | 0000906 | molecular_function | 6,7-dimethyl-8-ribityllumazine synthase activity |
| E | 0005829 | cellular_component | cytosol |
| E | 0009231 | biological_process | riboflavin biosynthetic process |
| E | 0009349 | cellular_component | riboflavin synthase complex |
| E | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA B 301 |
| Chain | Residue |
| A | ALA157 |
| B | ASP65 |
| B | ASP68 |
| B | ASN69 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA B 302 |
| Chain | Residue |
| A | GLU73 |
| B | ALA67 |
| B | GLU73 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA E 303 |
| Chain | Residue |
| E | GLU124 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CA A 304 |
| Chain | Residue |
| A | GLU124 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 305 |
| Chain | Residue |
| B | GLU40 |
| B | HOH546 |
| B | HOH547 |
| E | TYR45 |
| E | ASP46 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00178 |
| Chain | Residue | Details |
| A | HIS90 | |
| B | HIS90 | |
| C | HIS90 | |
| D | HIS90 | |
| E | HIS90 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00178 |
| Chain | Residue | Details |
| A | PHE22 | |
| B | THR82 | |
| B | GLU87 | |
| B | ASN115 | |
| B | HIS129 | |
| B | LYS137 | |
| C | PHE22 | |
| C | ALA53 | |
| C | THR82 | |
| C | GLU87 | |
| C | ASN115 | |
| A | ALA53 | |
| C | HIS129 | |
| C | LYS137 | |
| D | PHE22 | |
| D | ALA53 | |
| D | THR82 | |
| D | GLU87 | |
| D | ASN115 | |
| D | HIS129 | |
| D | LYS137 | |
| E | PHE22 | |
| A | THR82 | |
| E | ALA53 | |
| E | THR82 | |
| E | GLU87 | |
| E | ASN115 | |
| E | HIS129 | |
| E | LYS137 | |
| A | GLU87 | |
| A | ASN115 | |
| A | HIS129 | |
| A | LYS137 | |
| B | PHE22 | |
| B | ALA53 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| A | HIS90 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| B | HIS90 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| C | HIS90 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| D | HIS90 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1rvv |
| Chain | Residue | Details |
| E | HIS90 |
