2HW1

Crystal structure of human ketohexokinase complexed to different sugar molecules

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004454	molecular_function	ketohexokinase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006000	biological_process	fructose metabolic process
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0009744	biological_process	response to sucrose
A	0009749	biological_process	response to glucose
A	0009750	biological_process	response to fructose
A	0010043	biological_process	response to zinc ion
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0032868	biological_process	response to insulin
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0046835	biological_process	carbohydrate phosphorylation
A	0070061	molecular_function	fructose binding
A	0070062	cellular_component	extracellular exosome
A	0070873	biological_process	regulation of glycogen metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269\|PubMed:19237742, ECO:0007744\|PDB:2HW1

Chain	Residue	Details
A	ASP15

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000305\|PubMed:19237742, ECO:0007744\|PDB:2HW1

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1lio

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1lio