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2HUV

Crystal structure of PH0725 from Pyrococcus horikoshii OT3

Functional Information from GO Data
ChainGOidnamespacecontents
A0004164molecular_functiondiphthine synthase activity
A0008168molecular_functionmethyltransferase activity
A0017183biological_processprotein histidyl modification to diphthamide
A0032259biological_processmethylation
B0004164molecular_functiondiphthine synthase activity
B0008168molecular_functionmethyltransferase activity
B0017183biological_processprotein histidyl modification to diphthamide
B0032259biological_processmethylation
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE PT B 2001
ChainResidue
ATHR93
AHOH3080
AHOH3163
AHOH3164
BHIS126

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE PT B 2002
ChainResidue
BHOH2018
BHOH2040
BHOH2161

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 3001
ChainResidue
AHOH3002
AHOH3125
BHOH2007
BHOH2008
ATYR117

site_idAC4
Number of Residues19
DetailsBINDING SITE FOR RESIDUE SAH A 1001
ChainResidue
ALEU10
ATHR36
ASER37
AGLY86
AASP87
AVAL90
ASER115
AILE116
APHE165
ALEU166
ALEU206
AARG208
AALA209
APRO233
AHIS234
AILE235
AHOH3046
AHOH3055
AHOH3068

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues14
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01084, ECO:0000305|PubMed:18391406, ECO:0000305|Ref.4
ChainResidueDetails
ALEU10
BVAL90
BSER115
BLEU166
BALA209
BHIS234
AASP87
AVAL90
ASER115
ALEU166
AALA209
AHIS234
BLEU10
BASP87

226707

PDB entries from 2024-10-30

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