2HUU
Crystal structure of Aedes aegypti alanine glyoxylate aminotransferase in complex with alanine
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004760 | molecular_function | serine-pyruvate transaminase activity |
A | 0005777 | cellular_component | peroxisome |
A | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
A | 0008483 | molecular_function | transaminase activity |
A | 0009436 | biological_process | glyoxylate catabolic process |
A | 0016740 | molecular_function | transferase activity |
A | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 0004760 | molecular_function | serine-pyruvate transaminase activity |
B | 0005777 | cellular_component | peroxisome |
B | 0008453 | molecular_function | alanine-glyoxylate transaminase activity |
B | 0008483 | molecular_function | transaminase activity |
B | 0009436 | biological_process | glyoxylate catabolic process |
B | 0016740 | molecular_function | transferase activity |
B | 0019265 | biological_process | glycine biosynthetic process, by transamination of glyoxylate |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE ALA A 701 |
Chain | Residue |
A | PRO25 |
A | SER155 |
A | LLP206 |
A | LEU347 |
A | ARG356 |
B | HIS45 |
B | TYR257 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE 1BO B 801 |
Chain | Residue |
B | PRO25 |
B | SER155 |
B | ARG356 |
B | HOH1082 |
B | HOH1111 |
A | HIS45 |
A | TYR257 |
Functional Information from PROSITE/UniProt
site_id | PS00595 |
Number of Residues | 21 |
Details | AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. IDAMytGSQKvlgappGiTpV |
Chain | Residue | Details |
A | ILE197-VAL217 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | BINDING: in other chain => ECO:0000269|PubMed:16990263, ECO:0007744|PDB:2HUF, ECO:0007744|PDB:2HUI, ECO:0007744|PDB:2HUU |
Chain | Residue | Details |
A | SER78 | |
B | SER78 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16990263, ECO:0007744|PDB:2HUU |
Chain | Residue | Details |
A | SER155 | |
B | SER155 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: in other chain => ECO:0000269|PubMed:16990263, ECO:0007744|PDB:2HUI, ECO:0007744|PDB:2HUU |
Chain | Residue | Details |
A | GLN205 | |
B | GLN205 |
site_id | SWS_FT_FI4 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16990263, ECO:0007744|PDB:2HUI, ECO:0007744|PDB:2HUU |
Chain | Residue | Details |
A | TYR257 | |
A | THR260 | |
B | TYR257 | |
B | THR260 |
site_id | SWS_FT_FI5 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16990263, ECO:0007744|PDB:2HUI |
Chain | Residue | Details |
A | ARG356 | |
B | ARG356 |
site_id | SWS_FT_FI6 |
Number of Residues | 2 |
Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255|PIRSR:PIRSR000524-50, ECO:0000269|PubMed:16990263, ECO:0007744|PDB:2HUI, ECO:0007744|PDB:2HUU |
Chain | Residue | Details |
A | LLP206 | |
B | LLP206 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1bjo |
Chain | Residue | Details |
A | LEU51 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1bjo |
Chain | Residue | Details |
B | LEU51 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1bjo |
Chain | Residue | Details |
A | ASP180 | |
A | TRP105 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1bjo |
Chain | Residue | Details |
B | ASP180 | |
B | TRP105 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1bjo |
Chain | Residue | Details |
A | HIS104 | |
A | ASP180 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1bjo |
Chain | Residue | Details |
B | HIS104 | |
B | ASP180 |