2HTM

Crystal structure of TTHA0676 from Thermus thermophilus HB8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009228	biological_process	thiamine biosynthetic process
A	0009229	biological_process	thiamine diphosphate biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016783	molecular_function	sulfurtransferase activity
A	1990107	molecular_function	thiazole synthase activity
B	0005737	cellular_component	cytoplasm
B	0009228	biological_process	thiamine biosynthetic process
B	0009229	biological_process	thiamine diphosphate biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016783	molecular_function	sulfurtransferase activity
B	1990107	molecular_function	thiazole synthase activity
C	0005737	cellular_component	cytoplasm
C	0009228	biological_process	thiamine biosynthetic process
C	0009229	biological_process	thiamine diphosphate biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016783	molecular_function	sulfurtransferase activity
C	1990107	molecular_function	thiazole synthase activity
D	0005737	cellular_component	cytoplasm
D	0009228	biological_process	thiamine biosynthetic process
D	0009229	biological_process	thiamine diphosphate biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016783	molecular_function	sulfurtransferase activity
D	1990107	molecular_function	thiazole synthase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Schiff-base intermediate with DXP => ECO:0000255|HAMAP-Rule:MF_00443

Chain	Residue	Details
A	LYS96
B	LYS96
C	LYS96
D	LYS96

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00443

Chain	Residue	Details
A	GLY157
D	GLY157
D	ALA185
D	ASN207
A	ALA185
A	ASN207
B	GLY157
B	ALA185
B	ASN207
C	GLY157
C	ALA185
C	ASN207

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