2HS0
T. maritima PurL complexed with ATP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004642 | molecular_function | phosphoribosylformylglycinamidine synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 903 |
| Chain | Residue |
| A | ATP1065 |
| A | HOH1236 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 904 |
| Chain | Residue |
| A | ASP94 |
| A | GLN235 |
| A | ASP236 |
| A | ATP1066 |
| A | HOH1175 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ATP A 1065 |
| Chain | Residue |
| A | GLY136 |
| A | GLU137 |
| A | LEU138 |
| A | ARG139 |
| A | ALA366 |
| A | PHE370 |
| A | GLY386 |
| A | PHE387 |
| A | GLY388 |
| A | HIS405 |
| A | LYS429 |
| A | SER548 |
| A | SER549 |
| A | GLN550 |
| A | THR553 |
| A | THR555 |
| A | HIS556 |
| A | MG903 |
| A | HOH1112 |
| A | HOH1225 |
| A | HOH1236 |
| A | ASP107 |
| A | GLY135 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP A 1066 |
| Chain | Residue |
| A | TYR35 |
| A | ILE42 |
| A | LEU45 |
| A | LYS68 |
| A | GLU70 |
| A | ASP94 |
| A | GLN235 |
| A | ASP236 |
| A | GLU248 |
| A | ASN442 |
| A | VAL444 |
| A | SER476 |
| A | GLY477 |
| A | ASN478 |
| A | MG904 |
| A | HOH1108 |
| A | HOH1122 |
| A | HOH1175 |
Functional Information from PROSITE/UniProt
| site_id | PS01023 |
| Number of Residues | 13 |
| Details | PTR2_2 PTR2 family proton/oligopeptide symporters signature 2. TseLVAkGNLGAI |
| Chain | Residue | Details |
| A | THR246-ILE258 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00420","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17154526","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"17154526","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17154526","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18597481","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00420","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17154526","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 11 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17154526","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00420","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17154526","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18597481","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
