2HRO

Structure of the full-lenght Enzyme I of the PTS system from Staphylococcus carnosus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0008965	molecular_function	phosphoenolpyruvate-protein phosphotransferase activity
A	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016772	molecular_function	transferase activity, transferring phosphorus-containing groups
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 900

Chain	Residue
A	ARG297
A	ARG333
A	ASN455
A	ARG466

---

Functional Information from PROSITE/UniProt

site_id	PS00370
Number of Residues	12
Details	PEP_ENZYMES_PHOS_SITE PEP-utilizing enzymes phosphorylation site signature. GGrTsHSAIMSR

Chain	Residue	Details
A	GLY185-ARG196

---

site_id	PS00742
Number of Residues	19
Details	PEP_ENZYMES_2 PEP-utilizing enzymes signature 2. DfFSIGTNDLiQYTMAadR

Chain	Residue	Details
A	ASP448-ARG466

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Tele-phosphohistidine intermediate => ECO:0000250|UniProtKB:P08839, ECO:0000305|PubMed:16867985

Chain	Residue	Details
A	HIS190

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P08839, ECO:0000305|PubMed:16867985

Chain	Residue	Details
A	CYS503

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16867985

Chain	Residue	Details
A	ARG297
A	ARG333
A	ASN455
A	ARG466

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P08839

Chain	Residue	Details
A	GLU432
A	ASP456

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1kc7

Chain	Residue	Details
A	CYS503
A	HIS190

---

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1kc7

Chain	Residue	Details
A	THR169
A	HIS190

---