2HPI
Eubacterial and Eukaryotic Replicative DNA Polymerases are not Homologous: X-ray Structure of DNA Polymerase III
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006260 | biological_process | DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0071897 | biological_process | DNA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1221 |
| Chain | Residue |
| A | ASP20 |
| A | HIS47 |
| A | HIS214 |
| A | HOH1243 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 1222 |
| Chain | Residue |
| A | HIS11 |
| A | HIS13 |
| A | GLU72 |
| A | ASP212 |
| A | HOH1242 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1223 |
| Chain | Residue |
| A | ASP463 |
| A | ASP465 |
| A | LYS616 |
| A | MET617 |
| A | ASP618 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG A 1224 |
| Chain | Residue |
| A | GLU149 |
| A | ASP169 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1226 |
| Chain | Residue |
| A | GLY739 |
| A | MET804 |
