Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0009056 | biological_process | catabolic process |
| A | 0018625 | molecular_function | naphthalene 1,2-dioxygenase activity |
| A | 0044237 | biological_process | cellular metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051213 | molecular_function | dioxygenase activity |
| A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| B | 0009056 | biological_process | catabolic process |
| B | 0019380 | biological_process | 3-phenylpropionate catabolic process |
| B | 0051213 | molecular_function | dioxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FE A 450 |
| Chain | Residue |
| A | HIS208 |
| A | HIS213 |
| A | ASP362 |
| A | HOH1055 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 806 |
| Chain | Residue |
| B | HOH975 |
| B | GLN63 |
| B | GLN65 |
| B | HOH876 |
| B | HOH916 |
| B | HOH969 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 807 |
| Chain | Residue |
| B | GLY59 |
| B | SER60 |
| B | GLU167 |
| B | LYS172 |
| B | EDO823 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 810 |
| Chain | Residue |
| A | TRP439 |
| A | HIS440 |
| A | HOH899 |
| A | HOH965 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 828 |
| Chain | Residue |
| A | LEU128 |
| A | ASN129 |
| A | LYS130 |
| A | LYS131 |
| A | HOH1199 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FES A 829 |
| Chain | Residue |
| A | CYS81 |
| A | HIS83 |
| A | ARG84 |
| A | CYS101 |
| A | HIS104 |
| A | TRP106 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE AN3 A 801 |
| Chain | Residue |
| A | ASN201 |
| A | ASP205 |
| A | HIS208 |
| A | VAL209 |
| A | PHE224 |
| A | VAL260 |
| A | ASN297 |
| A | HOH1055 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 802 |
| Chain | Residue |
| B | TYR88 |
| B | GLN102 |
| B | MET191 |
| B | VAL192 |
| B | PHE193 |
| B | HOH848 |
| B | HOH852 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 803 |
| Chain | Residue |
| A | HOH1242 |
| B | ASN91 |
| B | GLN94 |
| B | HOH933 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 804 |
| Chain | Residue |
| B | ARG138 |
| B | ALA158 |
| B | GLU160 |
| B | PHE177 |
| B | VAL178 |
| B | ASP179 |
| B | EDO818 |
| B | HOH843 |
| site_id | BC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 805 |
| Chain | Residue |
| A | PRO49 |
| A | ALA50 |
| A | ASP53 |
| A | HOH939 |
| A | HOH1153 |
| A | HOH1301 |
| B | ARG78 |
| B | TYR79 |
| B | LYS80 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 808 |
| Chain | Residue |
| A | PRO118 |
| A | PHE119 |
| A | HOH1056 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 809 |
| Chain | Residue |
| B | GLU83 |
| B | ALA84 |
| B | ASN86 |
| B | HOH967 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 811 |
| Chain | Residue |
| A | THR56 |
| A | GLU92 |
| A | PRO186 |
| A | LYS188 |
| A | HOH1038 |
| B | GLU70 |
| B | ARG183 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 812 |
| Chain | Residue |
| A | ARG342 |
| A | ASP346 |
| A | HOH846 |
| A | HOH991 |
| B | ASN82 |
| B | HOH967 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 813 |
| Chain | Residue |
| A | THR368 |
| A | HOH957 |
| A | HOH968 |
| A | HOH1048 |
| B | ARG148 |
| B | HOH929 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 814 |
| Chain | Residue |
| A | LYS374 |
| A | HOH1118 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 815 |
| Chain | Residue |
| A | LYS136 |
| A | TYR376 |
| A | GLN377 |
| A | HOH843 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 816 |
| Chain | Residue |
| B | GLN186 |
| B | THR187 |
| B | HIS188 |
| B | HOH977 |
| A | VAL190 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 817 |
| Chain | Residue |
| A | SER73 |
| A | ILE74 |
| A | VAL141 |
| A | SER143 |
| A | HOH1168 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 818 |
| Chain | Residue |
| B | ASP46 |
| B | ARG115 |
| B | PHE116 |
| B | EDO804 |
| B | HOH896 |
| B | HOH936 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 819 |
| Chain | Residue |
| A | TRP254 |
| A | TYR399 |
| A | HOH1289 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 820 |
| Chain | Residue |
| A | SER177 |
| A | LYS276 |
| A | ARG279 |
| A | ASP335 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 821 |
| Chain | Residue |
| A | ASN4 |
| A | HIS29 |
| A | THR33 |
| A | VAL424 |
| A | SER425 |
| A | SER426 |
| A | HOH1285 |
| site_id | CC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 822 |
| site_id | CC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 823 |
| Chain | Residue |
| B | GLY59 |
| B | GLU61 |
| B | LYS164 |
| B | ARG165 |
| B | GLY166 |
| B | VAL174 |
| B | SO4807 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 824 |
| Chain | Residue |
| A | GLY98 |
| A | VAL100 |
| A | GLY107 |
| A | PHE108 |
| A | GLN115 |
| site_id | DC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 825 |
| Chain | Residue |
| B | ASN82 |
| B | HOH1030 |
| site_id | DC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 826 |
| Chain | Residue |
| A | LEU31 |
| A | PHE35 |
| A | ALA36 |
| A | MET59 |
| A | GLY60 |
| A | ILE61 |
| A | ASP62 |
| A | PHE152 |
| A | TYR376 |
| A | GLN377 |
| site_id | DC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 827 |
| Chain | Residue |
| A | HIS18 |
| A | VAL80 |
| A | CYS81 |
| A | ARG82 |
| A | SER381 |
| A | ASP382 |
| A | HOH839 |
| A | HOH869 |
| A | HOH889 |
Functional Information from PROSITE/UniProt
| site_id | PS00570 |
| Number of Residues | 24 |
| Details | RING_HYDROXYL_ALPHA Bacterial ring hydroxylating dioxygenases alpha-subunit signature. CrHRGktlvsveaGNakgfvCsYH |
| Chain | Residue | Details |
| A | CYS81-HIS104 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:16980501, ECO:0000269|Ref.3, ECO:0007744|PDB:2HMJ, ECO:0007744|PDB:2HMK, ECO:0007744|PDB:2HML, ECO:0007744|PDB:2HMM, ECO:0007744|PDB:2HMN, ECO:0007744|PDB:2HMO, ECO:0007744|PDB:4HJL, ECO:0007744|PDB:4HKV, ECO:0007744|PDB:4HM0, ECO:0007744|PDB:4HM1, ECO:0007744|PDB:4HM2, ECO:0007744|PDB:4HM3, ECO:0007744|PDB:4HM4, ECO:0007744|PDB:4HM5, ECO:0007744|PDB:4HM6, ECO:0007744|PDB:4HM7, ECO:0007744|PDB:4HM8 |
| Chain | Residue | Details |
| A | CYS81 | |
| A | HIS83 | |
| A | CYS101 | |
| A | HIS104 | |
| A | HIS208 | |
| A | HIS213 | |
| A | ASP362 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ndo |
| Chain | Residue | Details |
| A | HIS208 | |
| A | ASP205 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ndo |
| Chain | Residue | Details |
| A | HIS104 | |
