2HM2

Solution structure of ASC2

Functional Information from GO Data

Chain	GOid	namespace	contents
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0008385	cellular_component	IkappaB kinase complex
Q	0009968	biological_process	negative regulation of signal transduction
Q	0010804	biological_process	negative regulation of tumor necrosis factor-mediated signaling pathway
Q	0030291	molecular_function	protein serine/threonine kinase inhibitor activity
Q	0032088	biological_process	negative regulation of NF-kappaB transcription factor activity
Q	0032691	biological_process	negative regulation of interleukin-1 beta production
Q	0032731	biological_process	positive regulation of interleukin-1 beta production
Q	0043124	biological_process	negative regulation of canonical NF-kappaB signal transduction
Q	0045087	biological_process	innate immune response
Q	0120283	molecular_function	protein serine/threonine kinase binding
Q	1900226	biological_process	negative regulation of NLRP3 inflammasome complex assembly
Q	2000660	biological_process	negative regulation of interleukin-1-mediated signaling pathway