2HKQ
Crystal structure of the C-terminal domain of human EB1 in complex with the CAP-Gly domain of human Dynactin-1 (p150-Glued)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008017 | molecular_function | microtubule binding |
Functional Information from PROSITE/UniProt
| site_id | PS00845 |
| Number of Residues | 32 |
| Details | CAP_GLY_1 CAP-Gly domain signature. Gatlfatgk..WvGVilDeak....GKNdGTvqGrkYF |
| Chain | Residue | Details |
| B | GLY48-PHE79 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Region: {"description":"Interaction with APC","evidences":[{"source":"PubMed","id":"17293347","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 22 |
| Details | Region: {"description":"APC-binding","evidences":[{"source":"PubMed","id":"14514668","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 23 |
| Details | Region: {"description":"Interaction with SKA1","evidences":[{"source":"PubMed","id":"36592928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27225956","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23001180","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | Domain: {"description":"CAP-Gly","evidences":[{"source":"PROSITE-ProRule","id":"PRU00045","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
