2HJ4

Crystal structure of Alcaligenes faecalis AADH complex with p-nitrobenzylamine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
A	0030058	molecular_function	aliphatic amine dehydrogenase activity
A	0030059	molecular_function	aralkylamine dehydrogenase (azurin) activity
A	0042597	cellular_component	periplasmic space
B	0016491	molecular_function	oxidoreductase activity
B	0030058	molecular_function	aliphatic amine dehydrogenase activity
B	0030059	molecular_function	aralkylamine dehydrogenase (azurin) activity
B	0042597	cellular_component	periplasmic space
D	0009308	biological_process	amine metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016638	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors
D	0030059	molecular_function	aralkylamine dehydrogenase (azurin) activity
D	0042597	cellular_component	periplasmic space
H	0009308	biological_process	amine metabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0016638	molecular_function	oxidoreductase activity, acting on the CH-NH2 group of donors
H	0030059	molecular_function	aralkylamine dehydrogenase (azurin) activity
H	0042597	cellular_component	periplasmic space

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PNZ D 1201

Chain	Residue
B	LEU100
D	HOH1228
B	PHE123
B	ASN124
B	GLY178
D	ASP84
D	TRQ109
D	ASN156
D	VAL158
D	ASN159

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PNZ D 1202

Chain	Residue
B	TYR328
B	LEU380
B	GLY396
B	ALA421
B	SER422
B	LEU423
D	ASP84
D	ASN141
D	HOH1241
D	HOH1255

---

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE PNZ A 1203

Chain	Residue
A	LEU100
A	PHE123
A	ASN124
A	GLY178
A	LEU179
H	ASP84
H	TRQ109
H	ASN156
H	VAL158
H	ASN159
H	HOH1226
H	HOH1309

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PNZ H 1204

Chain	Residue
A	TYR328
A	LEU380
A	GLY396
A	ALA421
A	SER422
A	LEU423
H	ASP84
H	ASN141
H	HOH1250
H	HOH1321

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:16614214, ECO:0000269|PubMed:17005560, ECO:0000269|PubMed:17087503

Chain	Residue	Details
A	PHE97
A	LEU100
A	ASN124
B	PHE97
B	LEU100
B	ASN124

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000269|PubMed:16614214, ECO:0000269|PubMed:17005560

Chain	Residue	Details
D	ASP128
H	ASP128

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16614214, ECO:0000269|PubMed:17005560

Chain	Residue	Details
D	ASP84
D	ASN156
H	ASP84
H	ASN156

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	SITE: Transition state stabilizer

Chain	Residue	Details
D	THR172
H	THR172

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Tryptophylquinone => ECO:0000269|PubMed:16614214, ECO:0000269|PubMed:17005560, ECO:0000269|PubMed:17087503

Chain	Residue	Details
D	TRQ109
H	TRQ109

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	CROSSLNK: Tryptophan tryptophylquinone (Trp-Trp) => ECO:0000269|PubMed:16614214, ECO:0000269|PubMed:17005560, ECO:0000269|PubMed:17087503

Chain	Residue	Details
D	TRQ109
D	TRP160
H	TRQ109
H	TRP160

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 2bbk

Chain	Residue	Details
D	THR172
D	ASP84
D	PHE169
D	TRP160
D	ASP128

---

site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 2bbk

Chain	Residue	Details
H	THR172
H	ASP84
H	PHE169
H	TRP160
H	ASP128

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