Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 601 |
| Chain | Residue |
| A | ARG-1 |
| A | ARG120 |
| A | ASP122 |
| A | VAL123 |
| A | HOH1071 |
| A | HOH1090 |
| A | HOH1257 |
| A | HOH1265 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 603 |
| Chain | Residue |
| A | GLY20 |
| A | HOH1082 |
| A | HOH1270 |
| B | LYS10 |
| B | HOH1139 |
| A | TYR18 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | TYR18 |
| A | GLY187 |
| A | HIS188 |
| A | HOH1088 |
| A | HOH1296 |
| B | LYS44 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1002 |
| Chain | Residue |
| A | SER103 |
| A | SER103 |
| A | ARG106 |
| A | ARG106 |
| A | HOH1031 |
| A | HOH1096 |
| A | HOH1123 |
| A | HOH1123 |
| A | HOH1205 |
| A | HOH1205 |
| A | HOH1210 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GNQ B 901 |
| Chain | Residue |
| B | GLY23 |
| B | CYS25 |
| B | TRP26 |
| B | GLY62 |
| B | ASN67 |
| B | GLY68 |
| B | GLY69 |
| B | PHE70 |
| B | MET71 |
| B | GLY137 |
| B | VAL162 |
| B | ASN163 |
| B | HIS164 |
| B | PHE211 |
| B | HOH1086 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGACWAfSA |
| Chain | Residue | Details |
| A | GLN19-ALA30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
| Chain | Residue | Details |
| A | VAL162-GLY172 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWghnFGeeGYIrM |
| Chain | Residue | Details |
| A | TYR179-MET198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10088","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10089","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10090","evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | CYS25 | |
| A | ASN184 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | CYS25 | |
| B | ASN184 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | GLN19 | |
| A | CYS25 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | GLN19 | |
| B | CYS25 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | GLN19 | |
| A | ASN184 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | GLN19 | |
| B | ASN184 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | GLN19 | |
| A | CYS25 | |
| A | ASN184 | |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | GLN19 | |
| B | CYS25 | |
| B | ASN184 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| A | GLN19 | electrostatic stabiliser |
| A | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | HIS164 | proton acceptor, proton donor |
| A | ASN184 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| B | GLN19 | electrostatic stabiliser |
| B | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | HIS164 | proton acceptor, proton donor |
| B | ASN184 | electrostatic stabiliser |
