Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006508 | biological_process | proteolysis |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 601 |
| Chain | Residue |
| B | CYS25 |
| B | HIS164 |
| B | GNQ501 |
| B | CL801 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 602 |
| Chain | Residue |
| B | ASP139 |
| B | HIS142 |
| B | HOH882 |
| B | HOH933 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 603 |
| Chain | Residue |
| B | GLU15 |
| B | HIS188 |
| B | GLU193 |
| A | ASP173 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 701 |
| Chain | Residue |
| A | CYS25 |
| A | HIS164 |
| A | GNQ401 |
| A | CL802 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 702 |
| Chain | Residue |
| A | ASP139 |
| A | HIS142 |
| A | HOH803 |
| A | HOH940 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 703 |
| Chain | Residue |
| A | ASP3 |
| A | HOH864 |
| A | HOH926 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 801 |
| Chain | Residue |
| B | GLN19 |
| B | CYS25 |
| B | HIS164 |
| B | TRP186 |
| B | GNQ501 |
| B | ZN601 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 802 |
| Chain | Residue |
| A | GLN19 |
| A | CYS25 |
| A | HIS164 |
| A | TRP186 |
| A | GNQ401 |
| A | ZN701 |
| site_id | AC9 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GNQ A 401 |
| Chain | Residue |
| A | CYS25 |
| A | TRP26 |
| A | GLY62 |
| A | LYS64 |
| A | GLY68 |
| A | GLY69 |
| A | PHE70 |
| A | ALA140 |
| A | ARG141 |
| A | HIS142 |
| A | TYR154 |
| A | VAL162 |
| A | ASN163 |
| A | HIS164 |
| A | GLY165 |
| A | TRP186 |
| A | PHE211 |
| A | ZN701 |
| A | CL802 |
| A | HOH892 |
| B | HIS142 |
| B | PRO143 |
| B | PHE146 |
| B | GNQ501 |
| site_id | BC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE GNQ B 501 |
| Chain | Residue |
| A | HIS142 |
| A | PRO143 |
| A | PHE146 |
| A | GNQ401 |
| B | CYS25 |
| B | TRP26 |
| B | GLY62 |
| B | LYS64 |
| B | ASN67 |
| B | GLY68 |
| B | GLY69 |
| B | PHE70 |
| B | ALA140 |
| B | ARG141 |
| B | HIS142 |
| B | TYR154 |
| B | VAL162 |
| B | ASN163 |
| B | HIS164 |
| B | GLY165 |
| B | TRP186 |
| B | PHE211 |
| B | ZN601 |
| B | CL801 |
Functional Information from PROSITE/UniProt
| site_id | PS00139 |
| Number of Residues | 12 |
| Details | THIOL_PROTEASE_CYS Eukaryotic thiol (cysteine) proteases cysteine active site. QGsCGACWAfSA |
| Chain | Residue | Details |
| B | GLN19-ALA30 | |
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. VNHGVLVVGYG |
| Chain | Residue | Details |
| B | VAL162-GLY172 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWLvKNSWghnFGeeGYIrM |
| Chain | Residue | Details |
| B | TYR179-MET198 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | CYS25 | |
| B | ASN184 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | CYS25 | |
| A | ASN184 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | GLN19 | |
| B | CYS25 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | GLN19 | |
| A | CYS25 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | GLN19 | |
| B | ASN184 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | GLN19 | |
| A | ASN184 | |
| site_id | CSA7 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| B | HIS164 | |
| B | GLN19 | |
| B | CYS25 | |
| B | ASN184 | |
| site_id | CSA8 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1pad |
| Chain | Residue | Details |
| A | HIS164 | |
| A | GLN19 | |
| A | CYS25 | |
| A | ASN184 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| A | GLN19 | electrostatic stabiliser |
| A | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | HIS164 | proton acceptor, proton donor |
| A | ASN184 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 814 |
| Chain | Residue | Details |
| B | GLN19 | electrostatic stabiliser |
| B | CYS25 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | HIS164 | proton acceptor, proton donor |
| B | ASN184 | electrostatic stabiliser |
