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2HFH

THE NMR STRUCTURES OF A WINGED HELIX PROTEIN: GENESIS, 20 STRUCTURES

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
A0000981molecular_functionDNA-binding transcription factor activity, RNA polymerase II-specific
A0001701biological_processin utero embryonic development
A0003677molecular_functionDNA binding
A0003690molecular_functiondouble-stranded DNA binding
A0003700molecular_functionDNA-binding transcription factor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
A0006357biological_processregulation of transcription by RNA polymerase II
A0009653biological_processanatomical structure morphogenesis
A0030154biological_processcell differentiation
A0043565molecular_functionsequence-specific DNA binding
A0045944biological_processpositive regulation of transcription by RNA polymerase II
Functional Information from PROSITE/UniProt
site_idPS00657
Number of Residues14
DetailsFORK_HEAD_1 Fork head domain signature 1. KPPYSYiaLitm.AI
ChainResidueDetails
ALYS3-ILE16

site_idPS00658
Number of Residues7
DetailsFORK_HEAD_2 Fork head domain signature 2. WQNSIRH
ChainResidueDetails
ATRP47-HIS53

251801

PDB entries from 2026-04-08

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