2HFE

Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005249	molecular_function	voltage-gated potassium channel activity
C	0006813	biological_process	potassium ion transport
C	0008076	cellular_component	voltage-gated potassium channel complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE RB C 201

Chain	Residue
C	TYR78
C	TYR78
C	TYR78
C	TYR78

---

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE RB C 202

Chain	Residue
C	GLY77
C	GLY77
C	GLY77
C	RB203
C	RB203
C	RB203
C	RB203
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	GLY77

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE RB C 203

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	VAL76
C	VAL76
C	VAL76
C	VAL76
C	RB202
C	RB202
C	RB202
C	RB202
C	RB204
C	RB204
C	RB204
C	RB204

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE RB C 204

Chain	Residue
C	THR75
C	THR75
C	THR75
C	THR75
C	RB203
C	RB203
C	RB203
C	RB203

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOA C 79

Chain	Residue
C	GLY77
C	TYR78
C	TYR78
C	ASP80
C	LEU81
C	TYR82

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE B3H C 206

Chain	Residue
C	HOH302
C	PRO63
C	CYS70
C	LEU86
C	ARG89
C	LEU90
C	VAL93

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
B	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	45
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Intramembrane: {"description":"Helical; Pore-forming","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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