2HDE

Solution Structure of Human SAP18

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000118	cellular_component	histone deacetylase complex
A	0000381	biological_process	regulation of alternative mRNA splicing, via spliceosome
A	0003714	molecular_function	transcription corepressor activity
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006397	biological_process	mRNA processing
A	0008380	biological_process	RNA splicing
A	0016604	cellular_component	nuclear body
A	0016607	cellular_component	nuclear speck
A	0035145	cellular_component	exon-exon junction complex
A	0043065	biological_process	positive regulation of apoptotic process
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0048025	biological_process	negative regulation of mRNA splicing, via spliceosome
A	0050684	biological_process	regulation of mRNA processing
A	0061574	cellular_component	ASAP complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	13
Details	Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25218447","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25772364","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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