2HCB

Structure of AMPPCP-bound DnaA from Aquifex aeolicus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003688	molecular_function	DNA replication origin binding
A	0005524	molecular_function	ATP binding
A	0006270	biological_process	DNA replication initiation
A	0006275	biological_process	regulation of DNA replication
A	0016887	molecular_function	ATP hydrolysis activity
A	0043565	molecular_function	sequence-specific DNA binding
B	0003677	molecular_function	DNA binding
B	0003688	molecular_function	DNA replication origin binding
B	0005524	molecular_function	ATP binding
B	0006270	biological_process	DNA replication initiation
B	0006275	biological_process	regulation of DNA replication
B	0016887	molecular_function	ATP hydrolysis activity
B	0043565	molecular_function	sequence-specific DNA binding
C	0003677	molecular_function	DNA binding
C	0003688	molecular_function	DNA replication origin binding
C	0005524	molecular_function	ATP binding
C	0006270	biological_process	DNA replication initiation
C	0006275	biological_process	regulation of DNA replication
C	0016887	molecular_function	ATP hydrolysis activity
C	0043565	molecular_function	sequence-specific DNA binding
D	0003677	molecular_function	DNA binding
D	0003688	molecular_function	DNA replication origin binding
D	0005524	molecular_function	ATP binding
D	0006270	biological_process	DNA replication initiation
D	0006275	biological_process	regulation of DNA replication
D	0016887	molecular_function	ATP hydrolysis activity
D	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 400

Chain	Residue
A	THR126
A	ASP180
A	ASP181
A	ACP700

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG B 401

Chain	Residue
B	THR126
B	ASP181
B	ACP700

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 402

Chain	Residue
C	ASP181
C	ACP700
C	LYS125
C	THR126

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG D 403

Chain	Residue
D	LYS125
D	THR126
D	ASP180
D	ASP181
D	ACP700

---

site_id	AC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ACP A 700

Chain	Residue
A	TYR83
A	PHE88
A	ILE89
A	ASN94
A	VAL121
A	GLY122
A	THR123
A	GLY124
A	LYS125
A	THR126
A	HIS127
A	ASP181
A	VAL276
A	ARG277
A	GLU280
A	MG400
D	ARG230

---

site_id	AC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE ACP B 700

Chain	Residue
A	ARG230
B	TYR83
B	ASN87
B	PHE88
B	ILE89
B	ASN94
B	VAL121
B	GLY122
B	THR123
B	GLY124
B	LYS125
B	THR126
B	HIS127
B	ASP181
B	LYS253
B	VAL276
B	ARG277
B	GLU280
B	MG401

---

site_id	AC7
Number of Residues	18
Details	BINDING SITE FOR RESIDUE ACP C 700

Chain	Residue
B	ARG230
C	ASN87
C	PHE88
C	ILE89
C	ASN94
C	VAL121
C	GLY122
C	THR123
C	GLY124
C	LYS125
C	THR126
C	HIS127
C	ASP181
C	LYS253
C	VAL276
C	ARG277
C	GLU280
C	MG402

---

site_id	AC8
Number of Residues	17
Details	BINDING SITE FOR RESIDUE ACP D 700

Chain	Residue
C	ARG230
D	PHE88
D	ILE89
D	ASN94
D	VAL121
D	GLY122
D	THR123
D	GLY124
D	LYS125
D	THR126
D	HIS127
D	ASP181
D	LYS253
D	VAL276
D	ARG277
D	GLU280
D	MG403

---

Functional Information from PROSITE/UniProt

site_id	PS01008
Number of Residues	20
Details	DNAA DnaA protein signature. IAraFKrKdHTTVihAirsV

Chain	Residue	Details
A	ILE354-VAL373

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255

Chain	Residue	Details
A	GLY119
B	GLY119
C	GLY119
D	GLY119

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