2HB8

Crystal structure of VDR LBD in complex with 2alpha-methyl calcitriol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE MVD A 1001

Chain	Residue
A	TYR143
A	HIS305
A	LEU309
A	HIS397
A	LEU227
A	VAL234
A	SER237
A	ARG274
A	SER275
A	SER278
A	TRP286
A	CYS288

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:10678179, ECO:0000269|PubMed:11344298

Chain	Residue	Details
A	TYR143
A	LEU227
A	ILE271
A	HIS305
A	HIS397

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