Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004177 | molecular_function | aminopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0019538 | biological_process | protein metabolic process |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0040009 | biological_process | regulation of growth rate |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046662 | biological_process | regulation of egg-laying behavior |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0070006 | molecular_function | metalloaminopeptidase activity |
| B | 0004177 | molecular_function | aminopeptidase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0019538 | biological_process | protein metabolic process |
| B | 0030145 | molecular_function | manganese ion binding |
| B | 0040009 | biological_process | regulation of growth rate |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046662 | biological_process | regulation of egg-laying behavior |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0070006 | molecular_function | metalloaminopeptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 492 |
| Chain | Residue |
| B | LYS252 |
| B | ASP334 |
| B | ALA335 |
| B | GLU336 |
| B | GLY337 |
| B | ARG338 |
| B | LEU363 |
| B | NA3003 |
| B | NA3004 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 492 |
| Chain | Residue |
| A | LYS252 |
| A | ASP334 |
| A | ALA335 |
| A | GLU336 |
| A | GLY337 |
| A | ARG338 |
| A | LEU363 |
| A | NA3001 |
| A | NA3002 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 493 |
| Chain | Residue |
| A | LYS98 |
| A | ARG467 |
| A | HOH3196 |
| A | HOH3213 |
| A | HOH3497 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 494 |
| Chain | Residue |
| A | SER139 |
| A | GLY140 |
| A | ARG142 |
| A | NA3005 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 493 |
| Chain | Residue |
| B | SER139 |
| B | GLY140 |
| B | ARG142 |
| B | NA3006 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 494 |
| Chain | Residue |
| B | LYS98 |
| B | ARG467 |
| B | HOH3195 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 3001 |
| Chain | Residue |
| A | LYS252 |
| A | ASP257 |
| A | ASP275 |
| A | GLU336 |
| A | SO4492 |
| A | NA3002 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 3002 |
| Chain | Residue |
| A | ASP257 |
| A | ASP334 |
| A | GLU336 |
| A | SO4492 |
| A | NA3001 |
| A | HOH3379 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 3003 |
| Chain | Residue |
| B | LYS252 |
| B | ASP257 |
| B | ASP275 |
| B | GLU336 |
| B | SO4492 |
| B | NA3004 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 3004 |
| Chain | Residue |
| B | ASP257 |
| B | ASP334 |
| B | GLU336 |
| B | SO4492 |
| B | NA3003 |
| B | HOH3300 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA A 3005 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA B 3006 |
| site_id | BC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 2001 |
| Chain | Residue |
| A | PRO66 |
| A | HIS73 |
| A | HOH3270 |
| A | HOH3471 |
| B | ARG64 |
| B | PRO66 |
| B | HIS73 |
| B | HOH3423 |
| B | HOH3424 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2002 |
| Chain | Residue |
| A | ALA115 |
| A | GLU116 |
| A | VAL151 |
| A | ASP153 |
| A | HOH3412 |
| A | HOH3489 |
| site_id | BC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 2003 |
| site_id | BC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 2004 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2005 |
| Chain | Residue |
| A | LYS326 |
| A | ALA443 |
| A | PHE447 |
| A | HOH3188 |
| A | HOH3405 |
| A | HOH3414 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 2006 |
| Chain | Residue |
| B | LYS326 |
| B | ALA443 |
| B | PHE447 |
| B | HOH3415 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2007 |
| Chain | Residue |
| A | TYR117 |
| A | PRO118 |
| A | MET488 |
| A | LYS490 |
| A | HOH3025 |
| A | HOH3435 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2008 |
| Chain | Residue |
| A | HOH3342 |
| A | HOH3441 |
| A | THR138 |
| A | SER324 |
| A | LYS326 |
| A | HOH3190 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 2009 |
| Chain | Residue |
| B | THR2 |
| B | LYS133 |
| B | HOH3058 |
| B | HOH3280 |
| B | HOH3317 |
| site_id | CC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2010 |
| Chain | Residue |
| A | THR2 |
| A | GLN3 |
| A | LYS133 |
| A | HOH3008 |
| A | HOH3335 |
| A | HOH3346 |
| A | HOH3425 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 2011 |
| Chain | Residue |
| B | GLU245 |
| B | GLU388 |
| B | ARG452 |
| B | LEU480 |
| B | LYS482 |
| B | TYR483 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 2012 |
| Chain | Residue |
| A | ILE247 |
| A | THR356 |
| A | GLU388 |
| A | ARG452 |
| A | LEU480 |
| A | LYS482 |
| A | TYR483 |
Functional Information from PROSITE/UniProt
| site_id | PS00631 |
| Number of Residues | 8 |
| Details | CYTOSOL_AP Cytosol aminopeptidase signature. NTDAEGRL |
| Chain | Residue | Details |
| A | ASN332-LEU339 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS264 | |
| A | ARG338 | |
| B | LYS264 | |
| B | ARG338 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS252 | |
| B | GLU336 | |
| A | ASP257 | |
| A | ASP275 | |
| A | ASP334 | |
| A | GLU336 | |
| B | LYS252 | |
| B | ASP257 | |
| B | ASP275 | |
| B | ASP334 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1lam |
| Chain | Residue | Details |
| A | ARG338 | |
| A | LYS264 | |
| A | ASP257 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1lam |
| Chain | Residue | Details |
| B | ARG338 | |
| B | LYS264 | |
| B | ASP257 | |
