2HAY
The Crystal Structure of the Putative NAD(P)H-Flavin Oxidoreductase from Streptococcus pyogenes M1 GAS
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| A | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| B | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005829 | cellular_component | cytosol |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| C | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005829 | cellular_component | cytosol |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046256 | biological_process | 2,4,6-trinitrotoluene catabolic process |
| D | 0046857 | molecular_function | oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 801 |
| Chain | Residue |
| A | LYS89 |
| A | HIS90 |
| A | HOH892 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 802 |
| Chain | Residue |
| A | ARG20 |
| A | TRP70 |
| A | FMN702 |
| B | ARG105 |
| B | ARG116 |
| B | TYR120 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 803 |
| Chain | Residue |
| B | ARG202 |
| B | PRO204 |
| B | LYS205 |
| B | HIS206 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 D 804 |
| Chain | Residue |
| C | ARG135 |
| C | PHE138 |
| C | ASP139 |
| C | TYR171 |
| C | HOH717 |
| D | MSE128 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 805 |
| Chain | Residue |
| A | ARG202 |
| A | HOH939 |
| D | LYS23 |
| D | GLU24 |
| D | GLU25 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FMN B 701 |
| Chain | Residue |
| A | PRO43 |
| A | SER44 |
| A | SER45 |
| A | ARG105 |
| A | GLN144 |
| A | ILE147 |
| A | HOH806 |
| B | ARG16 |
| B | THR17 |
| B | ALA18 |
| B | GLY71 |
| B | PRO165 |
| B | ILE166 |
| B | GLU167 |
| B | GLY168 |
| B | GLN208 |
| B | ARG210 |
| B | HOH871 |
| B | HOH947 |
| site_id | AC7 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE FMN A 702 |
| Chain | Residue |
| A | ARG16 |
| A | THR17 |
| A | ALA18 |
| A | ARG20 |
| A | GLY71 |
| A | GLN75 |
| A | TYR146 |
| A | CYS164 |
| A | PRO165 |
| A | ILE166 |
| A | GLU167 |
| A | GLY168 |
| A | ARG210 |
| A | HOH824 |
| A | HOH875 |
| A | HOH915 |
| A | HOH941 |
| A | HOH943 |
| B | PRO43 |
| B | SER44 |
| B | SER45 |
| B | GLN144 |
| B | ILE147 |
| B | SO4802 |
| B | HOH890 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE FMN D 703 |
| Chain | Residue |
| C | PRO43 |
| C | SER44 |
| C | SER45 |
| C | GLN144 |
| C | ILE147 |
| C | HOH712 |
| D | ARG16 |
| D | THR17 |
| D | ALA18 |
| D | GLY71 |
| D | GLN75 |
| D | TYR146 |
| D | CYS164 |
| D | PRO165 |
| D | ILE166 |
| D | GLU167 |
| D | GLY168 |
| D | ARG210 |
| D | HOH880 |
| D | HOH886 |
| D | HOH907 |
| site_id | AC9 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE FMN C 704 |
| Chain | Residue |
| C | GLU167 |
| C | GLY168 |
| C | ARG210 |
| C | HOH828 |
| D | PRO43 |
| D | SER44 |
| D | SER45 |
| D | GLN144 |
| D | ILE147 |
| C | ARG16 |
| C | THR17 |
| C | ALA18 |
| C | ARG20 |
| C | GLY71 |
| C | GLN75 |
| C | TYR146 |
| C | CYS164 |
| C | PRO165 |
| C | ILE166 |
