2HAE
Crystal structure of a putative malic enzyme (malate oxidoreductase)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004470 | molecular_function | malic enzyme activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004470 | molecular_function | malic enzyme activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004470 | molecular_function | malic enzyme activity |
| C | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051287 | molecular_function | NAD binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004470 | molecular_function | malic enzyme activity |
| D | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 800 |
| Chain | Residue |
| D | LYS87 |
| D | GLU129 |
| D | ASP130 |
| D | ASP155 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE NAD A 501 |
| Chain | Residue |
| B | ALA191 |
| B | ASP211 |
| B | ARG212 |
| B | VAL258 |
| B | SER259 |
| B | ARG260 |
| B | LEU281 |
| B | ALA282 |
| B | ASN283 |
| B | ASN314 |
| B | HOH533 |
| A | HOH527 |
| B | THR159 |
| B | ASN186 |
| B | GLY189 |
| B | ALA190 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NAD B 501 |
| Chain | Residue |
| A | THR159 |
| A | ASN186 |
| A | ILE188 |
| A | GLY189 |
| A | ALA190 |
| A | ALA191 |
| A | ASP211 |
| A | ARG212 |
| A | VAL258 |
| A | SER259 |
| A | ARG260 |
| A | LEU281 |
| A | ALA282 |
| A | ASN283 |
| A | ASN314 |
| A | HOH513 |
| B | HOH530 |
| site_id | AC4 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAD C 501 |
| Chain | Residue |
| C | THR159 |
| C | ASN186 |
| C | GLY187 |
| C | ILE188 |
| C | GLY189 |
| C | ALA190 |
| C | ALA191 |
| C | VAL210 |
| C | ASP211 |
| C | ARG212 |
| C | VAL258 |
| C | SER259 |
| C | ARG260 |
| C | ILE263 |
| C | LEU281 |
| C | ALA282 |
| C | ASN283 |
| C | VAL312 |
| C | ASN314 |
| C | HOH503 |
| C | HOH515 |
| C | HOH517 |
| C | HOH524 |
| C | HOH545 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| A | ASP154 | |
| A | TYR32 | |
| A | LYS87 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| B | ASP154 | |
| B | TYR32 | |
| B | LYS87 |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| C | ASP154 | |
| C | TYR32 | |
| C | LYS87 |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1do8 |
| Chain | Residue | Details |
| D | ASP154 | |
| D | TYR32 | |
| D | LYS87 |
