2H9D

Pyruvate-Bound Structure of the Isochorismate-Pyruvate Lyase from Pseudomonas aerugionsa

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004106	molecular_function	chorismate mutase activity
A	0009697	biological_process	salicylic acid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016835	molecular_function	carbon-oxygen lyase activity
A	0016853	molecular_function	isomerase activity
A	0019752	biological_process	carboxylic acid metabolic process
A	0042864	biological_process	pyochelin biosynthetic process
A	0043904	molecular_function	isochorismate pyruvate lyase activity
A	0046417	biological_process	chorismate metabolic process
B	0004106	molecular_function	chorismate mutase activity
B	0009697	biological_process	salicylic acid biosynthetic process
B	0016829	molecular_function	lyase activity
B	0016835	molecular_function	carbon-oxygen lyase activity
B	0016853	molecular_function	isomerase activity
B	0019752	biological_process	carboxylic acid metabolic process
B	0042864	biological_process	pyochelin biosynthetic process
B	0043904	molecular_function	isochorismate pyruvate lyase activity
B	0046417	biological_process	chorismate metabolic process
C	0004106	molecular_function	chorismate mutase activity
C	0009697	biological_process	salicylic acid biosynthetic process
C	0016829	molecular_function	lyase activity
C	0016835	molecular_function	carbon-oxygen lyase activity
C	0016853	molecular_function	isomerase activity
C	0019752	biological_process	carboxylic acid metabolic process
C	0042864	biological_process	pyochelin biosynthetic process
C	0043904	molecular_function	isochorismate pyruvate lyase activity
C	0046417	biological_process	chorismate metabolic process
D	0004106	molecular_function	chorismate mutase activity
D	0009697	biological_process	salicylic acid biosynthetic process
D	0016829	molecular_function	lyase activity
D	0016835	molecular_function	carbon-oxygen lyase activity
D	0016853	molecular_function	isomerase activity
D	0019752	biological_process	carboxylic acid metabolic process
D	0042864	biological_process	pyochelin biosynthetic process
D	0043904	molecular_function	isochorismate pyruvate lyase activity
D	0046417	biological_process	chorismate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA D 301

Chain	Residue
A	GLU15
A	ASP18
C	HOH238
D	GLU15
D	ASP18
D	HOH343

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PYR C 201

Chain	Residue
D	LYS42
D	GLN90
D	PYR202
C	ARG14
C	HOH211
D	ALA38

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PYR D 202

Chain	Residue
C	PYR201
C	HOH211
D	ARG31
D	MET57
D	TYR86
D	ILE87
D	GLN90

---

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PYR C 203

Chain	Residue
C	ARG31
C	ARG53
C	MET57
C	TYR86
C	ILE87
C	PYR206
C	HOH249

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PYR B 204

Chain	Residue
B	ARG31
B	PRO49
B	MET57
B	ILE83
B	GLN90

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PYR A 205

Chain	Residue
A	ARG31
A	VAL35
A	MET57
A	TYR86
A	ILE87
A	HOH214

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PYR C 206

Chain	Residue
C	LYS42
C	ARG53
C	GLN90
C	PYR203
D	ARG14

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:16914555, ECO:0000269|PubMed:21751784

Chain	Residue	Details
A	ARG14
A	LYS42
B	ARG14
B	LYS42
C	ARG14
C	LYS42
D	ARG14
D	LYS42

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:16914555, ECO:0000269|PubMed:19432488, ECO:0000269|PubMed:21751784

Chain	Residue	Details
A	ARG31
A	GLN90
B	ARG31
B	GLN90
C	ARG31
C	GLN90
D	ARG31
D	GLN90

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