Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004707 | molecular_function | MAP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004707 | molecular_function | MAP kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ARG189 |
| A | ARG192 |
| A | TYR230 |
| B | THR255 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | LYS68 |
| A | ARG69 |
| A | ARG150 |
| A | GLU183 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 601 |
| Chain | Residue |
| B | ARG189 |
| B | ARG192 |
| B | TYR230 |
| A | THR255 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 602 |
| Chain | Residue |
| B | LYS68 |
| B | ARG69 |
| B | ARG150 |
| B | ARG174 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 893 A 901 |
| Chain | Residue |
| A | ILE32 |
| A | VAL40 |
| A | ALA42 |
| A | LYS55 |
| A | MET108 |
| A | LEU110 |
| A | MET111 |
| A | ASP112 |
| A | ALA113 |
| A | VAL158 |
| A | LEU168 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 893 B 902 |
| Chain | Residue |
| A | ARG50 |
| B | ILE32 |
| B | VAL40 |
| B | LYS55 |
| B | MET108 |
| B | LEU110 |
| B | MET111 |
| B | ASP112 |
| B | ALA113 |
| B | ASN114 |
| B | VAL158 |
| B | LEU168 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL A 701 |
| Chain | Residue |
| A | ILE197 |
| A | LEU198 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL B 702 |
| Chain | Residue |
| A | TYR230 |
| B | ILE197 |
| B | VAL256 |
Functional Information from PROSITE/UniProt
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IiHrDLKpsNIVV |
| Chain | Residue | Details |
| A | ILE147-VAL159 | |
| site_id | PS01351 |
| Number of Residues | 103 |
| Details | MAPK MAP kinase signature. FqnqthakrayRElvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmeldhermsyllyqmlcgikhlhsagiih..........RDlKpsnivvksdC |
| Chain | Residue | Details |
| A | PHE61-CYS163 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP151 | |
| B | ASP151 | |
| Chain | Residue | Details |
| A | ILE32 | |
| A | LYS55 | |
| B | ILE32 | |
| B | LYS55 | |
| Chain | Residue | Details |
| A | CYS116 | |
| B | CYS116 | |
| Chain | Residue | Details |
| A | GLU183 | |
| B | GLU183 | |
| Chain | Residue | Details |
| A | GLU185 | |
| B | GLU185 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | SER155 | |
| A | ASP151 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | SER155 | |
| B | ASP151 | |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP151 | |
| A | LYS153 | |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASP151 | |
| B | LYS153 | |
| site_id | CSA5 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP151 | |
| A | THR188 | |
| A | LYS153 | |
| site_id | CSA6 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASP151 | |
| B | THR188 | |
| B | LYS153 | |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASN156 | |
| A | ASP151 | |
| A | LYS153 | |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| B | ASN156 | |
| B | ASP151 | |
| B | LYS153 | |
