2H95
Structure of the Amantadine-Blocked Influenza A M2 Proton Channel Trans-membrane Domain by Solid-state NMR spectroscopy
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | SITE: Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter => ECO:0000255|HAMAP-Rule:MF_04069 |
| Chain | Residue | Details |
| A | HIS37 | |
| B | HIS37 | |
| C | HIS37 | |
| D | HIS37 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Seems to be involved in pH gating => ECO:0000255|HAMAP-Rule:MF_04069 |
| Chain | Residue | Details |
| A | TRP41 | |
| B | TRP41 | |
| C | TRP41 | |
| D | TRP41 |
