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2H95

Structure of the Amantadine-Blocked Influenza A M2 Proton Channel Trans-membrane Domain by Solid-state NMR spectroscopy

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsSite: {"description":"Essential for channel activity, possibly by being protonated during channel activation, and by forming the channel gate and the selective filter","evidences":[{"source":"HAMAP-Rule","id":"MF_04069","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues4
DetailsSite: {"description":"Seems to be involved in pH gating","evidences":[{"source":"HAMAP-Rule","id":"MF_04069","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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