2H92
Crystal Structure of Staphylococcus aureus Cytidine Monophosphate Kinase in complex with cytidine-5'-monophosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006220 | biological_process | pyrimidine nucleotide metabolic process |
| A | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0036430 | molecular_function | CMP kinase activity |
| A | 0036431 | molecular_function | dCMP kinase activity |
| A | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0006220 | biological_process | pyrimidine nucleotide metabolic process |
| B | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0036430 | molecular_function | CMP kinase activity |
| B | 0036431 | molecular_function | dCMP kinase activity |
| B | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| C | 0006220 | biological_process | pyrimidine nucleotide metabolic process |
| C | 0015949 | biological_process | nucleobase-containing small molecule interconversion |
| C | 0016301 | molecular_function | kinase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0036430 | molecular_function | CMP kinase activity |
| C | 0036431 | molecular_function | dCMP kinase activity |
| C | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1400 |
| Chain | Residue |
| A | ALA13 |
| A | ALA14 |
| A | GLY15 |
| A | LYS16 |
| A | SER17 |
| A | HOH1478 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1401 |
| Chain | Residue |
| B | LYS16 |
| B | SER17 |
| B | ARG153 |
| B | HOH1402 |
| B | HOH1438 |
| B | ALA13 |
| B | ALA14 |
| B | GLY15 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1402 |
| Chain | Residue |
| C | ALA13 |
| C | ALA14 |
| C | GLY15 |
| C | LYS16 |
| C | SER17 |
| C | ARG153 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE C5P A 1300 |
| Chain | Residue |
| A | THR34 |
| A | GLY35 |
| A | TYR38 |
| A | ARG39 |
| A | VAL95 |
| A | SER96 |
| A | ARG105 |
| A | GLY125 |
| A | ARG126 |
| A | ASP127 |
| A | ILE128 |
| A | ARG176 |
| A | ASP180 |
| A | ARG183 |
| A | HOH1402 |
| A | HOH1404 |
| A | HOH1405 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE C5P B 1301 |
| Chain | Residue |
| B | THR34 |
| B | GLY35 |
| B | TYR38 |
| B | ARG39 |
| B | VAL95 |
| B | SER96 |
| B | ALA99 |
| B | ARG105 |
| B | GLY125 |
| B | ARG126 |
| B | ASP127 |
| B | ARG176 |
| B | ASP180 |
| B | ARG183 |
| B | HOH1402 |
| B | HOH1406 |
| B | HOH1444 |
| B | HOH1493 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE C5P C 1302 |
| Chain | Residue |
| C | LYS16 |
| C | THR34 |
| C | GLY35 |
| C | TYR38 |
| C | ARG39 |
| C | VAL95 |
| C | SER96 |
| C | ALA99 |
| C | ARG105 |
| C | GLY125 |
| C | ARG126 |
| C | ASP127 |
| C | ARG176 |
| C | ASP180 |
| C | ARG183 |
| C | HOH1407 |
| C | HOH1413 |
| C | HOH1426 |
| C | HOH1494 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1001 |
| Chain | Residue |
| B | MET29 |
| B | ILE30 |
| B | TYR67 |
| B | LYS68 |
| B | ALA69 |
| B | LYS71 |
| B | LYS119 |
| B | GLY120 |
| B | ILE121 |
| B | HOH1492 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00238","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
