2H7Y
Pikromycin Thioesterase with covalent affinity label
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | ARG248 |
| B | GLU246 |
| B | GLU247 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 502 |
| Chain | Residue |
| A | ARG24 |
| B | ALA37 |
| B | GLN41 |
| B | ARG215 |
| B | HOH736 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | GLN41 |
| A | ARG215 |
| B | ARG24 |
| A | ALA37 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 506 |
| Chain | Residue |
| A | HIS254 |
| A | HIS254 |
| A | ASP256 |
| A | ASP256 |
| A | HOH620 |
| A | HOH620 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE DMS B 504 |
| Chain | Residue |
| A | ARG191 |
| A | GLN192 |
| A | ASP243 |
| A | HOH593 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE DMS B 505 |
| Chain | Residue |
| B | PRO179 |
| B | ARG227 |
| B | HIS254 |
| B | TRP255 |
| B | ASP256 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PSK A 548 |
| Chain | Residue |
| A | SER148 |
| A | GLY149 |
| A | HIS268 |
| A | HOH555 |
| A | HOH557 |
| A | HOH558 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PSK B 548 |
| Chain | Residue |
| B | SER148 |
| B | GLY149 |
| B | ILE186 |
| B | LEU220 |
| B | HIS268 |
| B | HOH556 |
| B | HOH557 |
| B | HOH558 |
| B | HOH561 |
| B | HOH619 |
| B | HOH701 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile; for thioesterase activity","evidences":[{"source":"UniProtKB","id":"Q03133","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"16969372","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16969373","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor; for thioesterase activity","evidences":[{"source":"UniProtKB","id":"Q03133","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"16969372","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16969373","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16969372","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16969372","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16969373","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q03133","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
