Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0015035 | molecular_function | protein-disulfide reductase activity |
| A | 0015036 | molecular_function | disulfide oxidoreductase activity |
| A | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0015035 | molecular_function | protein-disulfide reductase activity |
| B | 0015036 | molecular_function | disulfide oxidoreductase activity |
| B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MPD A 501 |
| Chain | Residue |
| A | ARG73 |
| A | HOH554 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MPD A 502 |
| Chain | Residue |
| A | HOH508 |
| A | ASP20 |
| A | GLY21 |
| A | ALA22 |
| A | GLY51 |
| A | LYS52 |
| A | LEU53 |
| A | THR54 |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL |
| Chain | Residue | Details |
| A | LEU24-LEU42 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile |
| Chain | Residue | Details |
| A | CYS32 | |
| A | CYS35 | |
| B | CYS32 | |
| B | CYS35 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Deprotonates C-terminal active site Cys |
| Chain | Residue | Details |
| A | ASP26 | |
| B | ASP26 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Contributes to redox potential value |
| Chain | Residue | Details |
| A | GLY33 | |
| A | PRO34 | |
| B | GLY33 | |
| B | PRO34 | |
| Chain | Residue | Details |
| A | LYS69 | |
| B | LYS69 | |
