2H6R

Crystal Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004807	molecular_function	triose-phosphate isomerase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006096	biological_process	glycolytic process
B	0004807	molecular_function	triose-phosphate isomerase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006096	biological_process	glycolytic process
C	0004807	molecular_function	triose-phosphate isomerase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006096	biological_process	glycolytic process
D	0004807	molecular_function	triose-phosphate isomerase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006094	biological_process	gluconeogenesis
D	0006096	biological_process	glycolytic process
E	0004807	molecular_function	triose-phosphate isomerase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0006094	biological_process	gluconeogenesis
E	0006096	biological_process	glycolytic process
F	0004807	molecular_function	triose-phosphate isomerase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0006094	biological_process	gluconeogenesis
F	0006096	biological_process	glycolytic process
G	0004807	molecular_function	triose-phosphate isomerase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0006094	biological_process	gluconeogenesis
G	0006096	biological_process	glycolytic process
H	0004807	molecular_function	triose-phosphate isomerase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0006094	biological_process	gluconeogenesis
H	0006096	biological_process	glycolytic process

Functional Information from PROSITE/UniProt

site_id	PS00171
Number of Residues	11
Details	TIM_1 Triosephosphate isomerase active site. AVEPPELIGTG

Chain	Residue	Details
A	ALA136-GLY146

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Electrophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	33
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00147","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
A	HIS90
A	ASN6
A	GLU138
A	LYS8

---

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
B	HIS90
B	ASN6
B	GLU138
B	LYS8

---

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
C	HIS90
C	ASN6
C	GLU138
C	LYS8

---

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
D	HIS90
D	ASN6
D	GLU138
D	LYS8

---

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
E	HIS90
E	ASN6
E	GLU138
E	LYS8

---

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
F	HIS90
F	ASN6
F	GLU138
F	LYS8

---

site_id	CSA7
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
G	HIS90
G	ASN6
G	GLU138
G	LYS8

---

site_id	CSA8
Number of Residues	4
Details	Annotated By Reference To The Literature 1hti

Chain	Residue	Details
H	HIS90
H	ASN6
H	GLU138
H	LYS8

---