2H2N

Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0017110	molecular_function	nucleoside diphosphate phosphatase activity
B	0005509	molecular_function	calcium ion binding
B	0017110	molecular_function	nucleoside diphosphate phosphatase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A 1000

Chain	Residue
A	SER98
A	ASP99
A	GLU145
A	GLU214
A	SER275
A	GLU326
A	HOH1070

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA B 1001

Chain	Residue
B	GLU145
B	GLU214
B	SER275
B	GLU326
B	HOH1081
B	SER98
B	ASP99

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT A 1002

Chain	Residue
A	VAL262
A	HOH1016

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15006348","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16835225","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S18","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S1D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2H2N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2H2U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15006348","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16835225","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S18","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2H2N","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2H2U","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	8
Details	Site: {"description":"Important for dimer formation","evidences":[{"source":"PubMed","id":"16835225","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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