2H2N
Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 1000 |
| Chain | Residue |
| A | SER98 |
| A | ASP99 |
| A | GLU145 |
| A | GLU214 |
| A | SER275 |
| A | GLU326 |
| A | HOH1070 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 1001 |
| Chain | Residue |
| B | GLU145 |
| B | GLU214 |
| B | SER275 |
| B | GLU326 |
| B | HOH1081 |
| B | SER98 |
| B | ASP99 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1002 |
| Chain | Residue |
| A | VAL262 |
| A | HOH1016 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15006348, ECO:0000269|PubMed:16835225, ECO:0007744|PDB:1S18, ECO:0007744|PDB:1S1D, ECO:0007744|PDB:2H2N, ECO:0007744|PDB:2H2U |
| Chain | Residue | Details |
| A | SER98 | |
| B | GLU326 | |
| A | GLU145 | |
| A | GLU214 | |
| A | SER275 | |
| A | GLU326 | |
| B | SER98 | |
| B | GLU145 | |
| B | GLU214 | |
| B | SER275 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15006348, ECO:0000269|PubMed:16835225, ECO:0007744|PDB:1S18, ECO:0007744|PDB:2H2N, ECO:0007744|PDB:2H2U |
| Chain | Residue | Details |
| A | ASP99 | |
| B | ASP99 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | SITE: Important for dimer formation => ECO:0000269|PubMed:16835225 |
| Chain | Residue | Details |
| A | GLU90 | |
| A | ILE130 | |
| A | SER132 | |
| A | SER186 | |
| B | GLU90 | |
| B | ILE130 | |
| B | SER132 | |
| B | SER186 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN18 | |
| B | ASN18 |
