2H00
Human methyltransferase 10 domain containing protein
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 402 |
| Chain | Residue |
| C | HOH451 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE SAH A 300 |
| Chain | Residue |
| A | GLU96 |
| A | VAL97 |
| A | ASP98 |
| A | CYS101 |
| A | GLN125 |
| A | THR127 |
| A | LEU128 |
| A | ASN147 |
| A | PRO149 |
| A | PHE190 |
| A | ASN8 |
| A | ARG193 |
| A | HOH2141 |
| A | HOH2143 |
| A | HOH2150 |
| A | HOH2159 |
| A | HOH2173 |
| A | HOH2192 |
| A | LEU38 |
| A | PRO40 |
| A | ARG45 |
| A | GLY73 |
| A | THR74 |
| A | GLY75 |
| A | THR95 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SAH B 301 |
| Chain | Residue |
| B | LEU38 |
| B | ARG45 |
| B | GLY73 |
| B | THR74 |
| B | GLY75 |
| B | THR95 |
| B | GLU96 |
| B | VAL97 |
| B | ASP98 |
| B | THR127 |
| B | LEU128 |
| B | ASN147 |
| B | PRO149 |
| B | HOH402 |
| B | HOH403 |
| B | HOH412 |
| B | HOH418 |
| B | HOH427 |
| C | ASN8 |
| C | HOH420 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SAH C 302 |
| Chain | Residue |
| B | ASN8 |
| B | HOH413 |
| B | HOH432 |
| C | LEU38 |
| C | ARG45 |
| C | GLY73 |
| C | THR74 |
| C | THR95 |
| C | GLU96 |
| C | VAL97 |
| C | ASP98 |
| C | LYS126 |
| C | ASN147 |
| C | PRO149 |
| C | PHE151 |
| C | HOH404 |
| C | HOH406 |
| C | HOH408 |
| C | HOH413 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DTU A 2140 |
| Chain | Residue |
| A | LYS106 |
| A | VAL109 |
| A | GLU110 |
| A | SER115 |
| A | ILE118 |
| A | VAL120 |
| A | HOH2153 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Region: {"description":"K-loop","evidences":[{"source":"PubMed","id":"30197297","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Region: {"description":"RNA-binding","evidences":[{"source":"PubMed","id":"30197297","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DU4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DU5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29593291","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30197299","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2006","submissionDatabase":"PDB data bank","title":"The crystal structure of human methyltransferase 10 domain-containing protein.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"2H00","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6B92","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GFN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30197299","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2006","submissionDatabase":"PDB data bank","title":"The crystal structure of human methyltransferase 10 domain-containing protein.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"2H00","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GFK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6GFN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30197299","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6GFN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
