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2GZF

Crystal structure of the E9 DNase domain with a mutant immunity protein IM9 (Y54F)

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0015643molecular_functiontoxic substance binding
A0019904molecular_functionprotein domain specific binding
A0030153biological_processbacteriocin immunity
A0032991cellular_componentprotein-containing complex
B0004519molecular_functionendonuclease activity
B0005102molecular_functionsignaling receptor binding
B0009617biological_processresponse to bacterium
B0019835biological_processcytolysis
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 301
ChainResidue
BHIS102
BHIS127
BHIS131
BPO4503

site_idAC2
Number of Residues13
DetailsBINDING SITE FOR RESIDUE PO4 B 503
ChainResidue
BHIS127
BHIS131
BZN301
BHOH518
BHOH527
BHOH577
BHOH579
BHOH687
ASER28
BARG5
BLEU101
BHIS102
BHIS103

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BHIS102
BHIS127
BHIS131

Catalytic Information from CSA
site_idMCSA1
Number of Residues7
DetailsM-CSA 791
ChainResidueDetails
BARG5electrostatic stabiliser
BARG96electrostatic stabiliser
BGLU100electrostatic stabiliser
BHIS102metal ligand
BHIS103increase nucleophilicity, proton acceptor, proton donor
BHIS127metal ligand
BHIS131metal ligand

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PDB entries from 2024-10-30

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