Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2GVN

L-asparaginase from Erwinia carotovora in complex with aspartic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004067	molecular_function	asparaginase activity
A	0006520	biological_process	amino acid metabolic process
A	0006528	biological_process	asparagine metabolic process
A	0016787	molecular_function	hydrolase activity
B	0004067	molecular_function	asparaginase activity
B	0006520	biological_process	amino acid metabolic process
B	0006528	biological_process	asparagine metabolic process
B	0016787	molecular_function	hydrolase activity
C	0004067	molecular_function	asparaginase activity
C	0006520	biological_process	amino acid metabolic process
C	0006528	biological_process	asparagine metabolic process
C	0016787	molecular_function	hydrolase activity
D	0004067	molecular_function	asparaginase activity
D	0006520	biological_process	amino acid metabolic process
D	0006528	biological_process	asparagine metabolic process
D	0016787	molecular_function	hydrolase activity
E	0004067	molecular_function	asparaginase activity
E	0006520	biological_process	amino acid metabolic process
E	0006528	biological_process	asparagine metabolic process
E	0016787	molecular_function	hydrolase activity
F	0004067	molecular_function	asparaginase activity
F	0006520	biological_process	amino acid metabolic process
F	0006528	biological_process	asparagine metabolic process
F	0016787	molecular_function	hydrolase activity
G	0004067	molecular_function	asparaginase activity
G	0006520	biological_process	amino acid metabolic process
G	0006528	biological_process	asparagine metabolic process
G	0016787	molecular_function	hydrolase activity
H	0004067	molecular_function	asparaginase activity
H	0006520	biological_process	amino acid metabolic process
H	0006528	biological_process	asparagine metabolic process
H	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ASP A 3350

Chain	Residue
A	GLY14
A	HOH3355
A	HOH3405
A	HOH3470
A	HOH3630
A	THR15
A	GLY61
A	SER62
A	GLU63
A	GLY94
A	THR95
A	ASP96
A	ALA120

site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ASP B 3351

Chain	Residue
B	GLY14
B	THR15
B	GLY61
B	SER62
B	GLU63
B	GLY94
B	THR95
B	ASP96
B	ALA120
B	HOH3383
B	HOH3396
B	HOH3520

site_id	AC3
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ASP E 3352

Chain	Residue
E	GLY14
E	THR15
E	GLY61
E	SER62
E	GLU63
E	GLY94
E	THR95
E	ASP96
E	ALA120
E	HOH3355
E	HOH3379
E	HOH3529

site_id	AC4
Number of Residues	12
Details	BINDING SITE FOR RESIDUE ASP F 3353

Chain	Residue
F	GLY14
F	THR15
F	GLY61
F	SER62
F	GLU63
F	GLY94
F	THR95
F	ASP96
F	ALA120
F	HOH3363
F	HOH3395
F	HOH3630

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ASP C 3354

Chain	Residue
C	GLY14
C	THR15
C	GLY61
C	SER62
C	GLU63
C	GLY94
C	THR95
C	ASP96
C	ALA120
C	HOH3363
C	HOH3386

site_id	AC6
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ASP D 3355

Chain	Residue
D	GLY14
D	THR15
D	GLY61
D	SER62
D	GLU63
D	GLY94
D	THR95
D	ASP96
D	ALA120
D	HOH3374
D	HOH3412
D	HOH3434
D	HOH3610

site_id	AC7
Number of Residues	11
Details	BINDING SITE FOR RESIDUE ASP G 3356

Chain	Residue
G	GLY14
G	THR15
G	GLY61
G	SER62
G	GLU63
G	GLY94
G	THR95
G	ASP96
G	ALA120
G	HOH3374
G	HOH3464

site_id	AC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE ASP H 3357

Chain	Residue
H	GLY14
H	THR15
H	GLY61
H	SER62
H	GLU63
H	GLY94
H	THR95
H	ASP96
H	ALA120
H	HOH3388
H	HOH3397
H	HOH3468
H	HOH3642

Functional Information from PROSITE/UniProt

site_id	PS00144
Number of Residues	9
Details	ASN_GLN_ASE_1 Asparaginase / glutaminase active site signature 1. IlATGGTIA

Chain	Residue	Details
A	ILE9-ALA17

site_id	PS00917
Number of Residues	11
Details	ASN_GLN_ASE_2 Asparaginase / glutaminase active site signature 2. GvVitHGTDTL

Chain	Residue	Details
A	GLY88-LEU98

Catalytic Information from CSA

site_id	CSA1
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
A	THR15
A	THR95
A	ASP96
A	TYR29
A	LYS168

site_id	CSA10
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
F	THR15
F	THR95
F	TYR29
B	GLN290

site_id	CSA11
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
C	GLN290
G	THR15
G	THR95
G	TYR29

site_id	CSA12
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
H	THR15
H	THR95
H	TYR29
D	GLN290

site_id	CSA13
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
A	THR15
A	THR95
A	TYR29
E	GLN290

site_id	CSA14
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
F	GLN290
B	THR15
B	THR95
B	TYR29

site_id	CSA15
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
C	THR15
C	THR95
C	TYR29
G	GLN290

site_id	CSA16
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
H	GLN290
D	THR15
D	THR95
D	TYR29

site_id	CSA17
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
A	GLY289

site_id	CSA18
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
B	GLY289

site_id	CSA19
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
C	GLY289

site_id	CSA2
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
B	THR15
B	THR95
B	ASP96
B	TYR29
B	LYS168

site_id	CSA20
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
D	GLY289

site_id	CSA21
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
E	GLY289

site_id	CSA22
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
F	GLY289

site_id	CSA23
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
G	GLY289

site_id	CSA24
Number of Residues	1
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
H	GLY289

site_id	CSA3
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
C	THR15
C	THR95
C	ASP96
C	TYR29
C	LYS168

site_id	CSA4
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
D	THR15
D	THR95
D	ASP96
D	TYR29
D	LYS168

site_id	CSA5
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
E	THR15
E	THR95
E	ASP96
E	TYR29
E	LYS168

site_id	CSA6
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
F	THR15
F	THR95
F	ASP96
F	TYR29
F	LYS168

site_id	CSA7
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
G	THR15
G	THR95
G	ASP96
G	TYR29
G	LYS168

site_id	CSA8
Number of Residues	5
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
H	THR15
H	THR95
H	ASP96
H	TYR29
H	LYS168

site_id	CSA9
Number of Residues	4
Details	Annotated By Reference To The Literature 3eca

Chain	Residue	Details
A	GLN290
E	THR15
E	THR95
E	TYR29

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)